Visfatin, Glucose Metabolism and Vascular Disease: a Review of Evidence

Overview

Journal Diabetol Metab Syndr

Publisher Biomed Central

Specialty Endocrinology

Date 2010 Mar 30

PMID 20346149

Citations 50

Authors

Pedro Saddi-Rosa

Carolina S V Oliveira

Fernando M A Giuffrida

Andre F Reis

Affiliations

Soon will be listed here.

Abstract

The adipose tissue is an endocrine organ producing substances called adipocytokines that have different effects on lipid metabolism, metabolic syndrome, and cardiovascular risk. Visfatin was recently described as an adipocytokine with potentially important effects on glucose metabolism and atherosclerosis. Visfatin has been linked to several inflammatory conditions, beta cell function, and cardiovascular disease. The growing number of publications on the subject shall bring further evidence about this adipocytokine. Its findings may contribute in the identification of higher risk individuals for diabetes and cardiovascular disease with a better comprehension about the complex intercorrelation between adiposity, glucose metabolism and vascular disease.

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