Loss of Susceptibility As a Novel Breeding Strategy for Durable and Broad-spectrum Resistance

Overview

Journal Mol Breed

Specialties Biotechnology
Molecular Biology

Date 2010 Mar 18

PMID 20234841

Citations 124

Authors

Stefano Pavan

Evert Jacobsen

Richard G F Visser

Yuling Bai

Affiliations

Soon will be listed here.

Abstract

Recent studies on plant immunity have suggested that a pathogen should suppress induced plant defense in order to infect a plant species, which otherwise would have been a nonhost to the pathogen. For this purpose, pathogens exploit effector molecules to interfere with different layers of plant defense responses. In this review, we summarize the latest findings on plant factors that are activated by pathogen effectors to suppress plant immunity. By looking from a different point of view into host and nonhost resistance, we propose a novel breeding strategy: disabling plant disease susceptibility genes (S-genes) to achieve durable and broad-spectrum resistance.

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