Pulmonary Cystic Echinococcosis

Overview

Journal Curr Opin Pulm Med

Specialty Pulmonary Medicine

Date 2010 Mar 11

PMID 20216420

Citations 49

Authors

Saul Santivanez

Hector H Garcia

Affiliations

Soon will be listed here.

Abstract

Purpose Of Review: Pulmonary cystic echinococcosis, a zoonosis caused by the larvae of the dog tapeworm Echinococcus granulosus, is considered as a major public health problem in countries where dogs are used to care for large herds. Despite its frequency and widespread endemicity, the literature on pulmonary cystic echinococcosis is scarce and not systematic. We aimed to summarize currently available information to provide a comprehensive overview for clinicians facing cases of pulmonary cystic echinococcosis.

Recent Findings: Despite discrepancies in the literature, some patterns can be discerned. The ratio of lung:liver involvement is higher in children than in adults. Most pulmonary cases are discovered incidentally on routine radiograph evaluation; also most infected individuals remain asymptomatic until the cyst enlarges sufficiently to cause symptoms. Symptoms are usually caused by mass effect from the cyst. Complications (cyst rupture, aggregated infection) change the clinical presentation, producing cough, chest pain, hemoptysis, or vomica. Diagnosis is obtained by chest radiographs or computed tomography, and supported by serology. Presurgical chemotherapy reduces the chances of seeding and recurrence. Treatment with benzimidazoles is an option when surgery is unavailable or complete removal is unfeasible.

Summary: Diagnosis of pulmonary cystic echinococcosis is primarily made by imaging, and surgery remains the main therapeutic approach.

Citing Articles

The impact of detailed history taking: a case report of pediatric pulmonary and hepatic hydatid disease from Ecuador.

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PMID: 39328588 PMC: 11425589. DOI: 10.3389/fped.2024.1457463.

HLA class II profile in patients with different stages of cystic echinococcosis according to the WHO ultrasound imaging classification.

Madih A, Ravari M, Yousefi M, Ehsan M, Akhlaghi E, Kamyabi H Parasitol Res. 2024; 123(9):330.

PMID: 39316156 DOI: 10.1007/s00436-024-08353-4.

Treatment of uncomplicated hepatic cystic echinococcosis (hydatid disease).

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Primary Pulmonary Echinococcosis in the United States: A Case Report and Review of the Literature.

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Delayed Surgical Treatment of a CE1 Lung Cyst Resulting in Pericystectomy of CE4 Cyst.

DAlessandro G, Pontarelli A, Leka A, Casazza D, Lissandrin R, Manciulli T Case Rep Infect Dis. 2024; 2024:5167805.

PMID: 38515562 PMC: 10957245. DOI: 10.1155/2024/5167805.

References

Stamatakos M, Sargedi C, Stefanaki C, Safioleas C, Matthaiopoulou I, Safioleas M . Anthelminthic treatment: an adjuvant therapeutic strategy against Echinococcus granulosus. Parasitol Int. 2009; 58(2):115-20. DOI: 10.1016/j.parint.2009.01.002. View

Haralabidis S, Diakou A, Frydas S, Papadopoulos E, Mylonas A, Patsias A . Long-term evaluation of patients with hydatidosis treated with albendazole and praziquantel. Int J Immunopathol Pharmacol. 2008; 21(2):429-35. DOI: 10.1177/039463200802100223. View

Siracusano A, Teggi A, Ortona E . Human cystic echinococcosis: old problems and new perspectives. Interdiscip Perspect Infect Dis. 2009; 2009:474368. PMC: 2771156. DOI: 10.1155/2009/474368. View

Turgut A, Altinok T, Topcu S, Kosar U . Local complications of hydatid disease involving thoracic cavity: imaging findings. Eur J Radiol. 2008; 70(1):49-56. DOI: 10.1016/j.ejrad.2008.01.002. View

Moro P, Schantz P . Echinococcosis: a review. Int J Infect Dis. 2008; 13(2):125-33. DOI: 10.1016/j.ijid.2008.03.037. View

Dopchiz M, Elissondo M, Andresiuk M, Maiorini E, Gutierrez A, Muzulin P . Pediatric hydatidosis in the south-east of the Buenos Aires province, Argentina. Rev Argent Microbiol. 2009; 41(2):105-11. View

Tatar D, Senol G, Gunes E, Unsal S, Perim G . Diagnosis and treatment of pulmonary cystic hydatidosis. Indian J Pediatr. 2008; 75(10):1003-7. DOI: 10.1007/s12098-008-0165-8. View

Arinc S, Alpay L, Okur E, Koksal C, Sogukpinar O, Kosif A . Recurrent pulmonary hydatid disease: analysis of ten cases. Surg Today. 2008; 38(11):983-6. DOI: 10.1007/s00595-008-3759-x. View

Garcia H, Moro P, Schantz P . Zoonotic helminth infections of humans: echinococcosis, cysticercosis and fascioliasis. Curr Opin Infect Dis. 2007; 20(5):489-94. DOI: 10.1097/QCO.0b013e3282a95e39. View

10.

Vasquez J, Montesinos E, Peralta J, Rojas L, Delarosa J, Leon J . Need for lung resection in patients with intact or ruptured hydatid cysts. Thorac Cardiovasc Surg. 2009; 57(5):295-302. DOI: 10.1055/s-0029-1185604. View

11.

Ahmadi N, Hamidi M . A retrospective analysis of human cystic echinococcosis in Hamedan province, an endemic region of Iran. Ann Trop Med Parasitol. 2008; 102(7):603-9. DOI: 10.1179/136485908X337517. View

12.

Hernandez-Gonzalez A, Muro A, Barrera I, Ramos G, Orduna A, Siles-Lucas M . Usefulness of four different Echinococcus granulosus recombinant antigens for serodiagnosis of unilocular hydatid disease (UHD) and postsurgical follow-up of patients treated for UHD. Clin Vaccine Immunol. 2007; 15(1):147-53. PMC: 2223859. DOI: 10.1128/CVI.00363-07. View

13.

Torgerson P, Deplazes P . Echinococcosis: diagnosis and diagnostic interpretation in population studies. Trends Parasitol. 2009; 25(4):164-70. DOI: 10.1016/j.pt.2008.12.008. View

14.

Gavidia C, Gonzalez A, Lopera L, Jayashi C, Angelats R, Barron E . Evaluation of nitazoxanide and oxfendazole efficacy against cystic echinococcosis in naturally infected sheep. Am J Trop Med Hyg. 2009; 80(3):367-72. PMC: 2673094. View

15.

Arroud M, Afifi M, El Ghazi K, Nejjari C, Bouabdallah Y . Lung hydatic cysts in children: comparison study between giant and non-giant cysts. Pediatr Surg Int. 2008; 25(1):37-40. DOI: 10.1007/s00383-008-2256-z. View

16.

Shehatha J, Alizzi A, Alward M, Konstantinov I . Thoracic hydatid disease; a review of 763 cases. Heart Lung Circ. 2008; 17(6):502-4. DOI: 10.1016/j.hlc.2008.04.001. View

17.

Zeyrek D, Savas R, Gulen F, Demir E, Tanac R . ''Air-bubble'' signs in the CT diagnosis of perforated pulmonary hydatid cyst: three case reports. Minerva Pediatr. 2008; 60(3):361-4. View

18.

Craig P, McManus D, Lightowlers M, Chabalgoity J, Garcia H, Gavidia C . Prevention and control of cystic echinococcosis. Lancet Infect Dis. 2007; 7(6):385-94. DOI: 10.1016/S1473-3099(07)70134-2. View

19.

Arinc S, Kosif A, Ertugrul M, Arpag H, Alpay L, Unal O . Evaluation of pulmonary hydatid cyst cases. Int J Surg. 2009; 7(3):192-5. DOI: 10.1016/j.ijsu.2008.11.003. View

20.

Brunetti E, Kern P, Vuitton D . Expert consensus for the diagnosis and treatment of cystic and alveolar echinococcosis in humans. Acta Trop. 2009; 114(1):1-16. DOI: 10.1016/j.actatropica.2009.11.001. View