Origin of Hepatitis Delta Virus

Overview

Journal Future Microbiol

Specialties Infectious Diseases
Microbiology

Date 2010 Mar 10

PMID 20210550

Citations 33

Authors

John Taylor

Martin Pelchat

Affiliations

Soon will be listed here.

Abstract

This article addresses some of the questions relating to how hepatitis delta virus (HDV), an agent so far unique in the animal world, might have arisen. HDV was discovered in patients infected with hepatitis B virus (HBV). It generally makes HBV infections more damaging to the liver. It is a subviral satellite agent that depends upon HBV envelope proteins for its assembly and ability to infect new cells. In other aspects of replication, HDV is both independent of and very different from HBV. In addition, the small single-stranded circular RNA genome of HDV, and its mechanism of replication, demonstrate an increasing number of similarities to the viroids - a large family of helper-independent subviral agents that cause pathogenesis in plants.

Citing Articles

Analysis of Replication, Cell Division-Mediated Spread, and HBV Envelope Protein-Dependent Pseudotyping of Three Mammalian Delta-like Agents.

Gnouamozi G, Zhang Z, Prasad V, Lauber C, Seitz S, Urban S Viruses. 2024; 16(6).

PMID: 38932152 PMC: 11209313. DOI: 10.3390/v16060859.

Hepatocyte Intrinsic Innate Antiviral Immunity against Hepatitis Delta Virus Infection: The Voices of Bona Fide Human Hepatocytes.

Woo Y, Ma M, Okawa M, Saito T Viruses. 2024; 16(5).

PMID: 38793622 PMC: 11126147. DOI: 10.3390/v16050740.

Highlights from the 2023 International Meeting on the Molecular Biology of Hepatitis B virus.

Allweiss L, Cohen C, Dias J, Fumagalli V, Guo H, Harris J J Gen Virol. 2024; 105(5).

PMID: 38757942 PMC: 11258880. DOI: 10.1099/jgv.0.001978.

Viroids of the Mediterranean Basin.

Kaponi M, Kyriakopoulou P, Hadidi A Viruses. 2024; 16(4).

PMID: 38675953 PMC: 11053799. DOI: 10.3390/v16040612.

The Remarkable Legacy of Theodor O. Diener (1921-2023): Preeminent Plant Pathologist and the Discoverer of Viroids.

Owens R, Hadidi A Viruses. 2023; 15(9).

PMID: 37766301 PMC: 10535727. DOI: 10.3390/v15091895.

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