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Martin Pelchat

Explore the profile of Martin Pelchat including associated specialties, affiliations and a list of published articles. Areas
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Articles 42
Citations 637
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Recent Articles
1.
Galipeau Y, Castonguay N, McCluskie P, Sonoda M, Keeshan A, Collins E, et al.
FASEB J . 2025 Feb; 39(4):e70390. PMID: 39950298
Clinical outcomes resulting from SARS-CoV-2 infection vary widely, ranging from asymptomatic cases to the development of mild to severe respiratory illness, and in some instances, chronic lingering disease and mortality....
2.
Overbey E, Kim J, Tierney B, Park J, Houerbi N, Lucaci A, et al.
Nature . 2024 Jun; 632(8027):1145-1154. PMID: 38862028
Spaceflight induces molecular, cellular and physiological shifts in astronauts and poses myriad biomedical challenges to the human body, which are becoming increasingly relevant as more humans venture into space. Yet...
3.
Collins E, Galipeau Y, Arnold C, Bhereur A, Booth R, Buchan A, et al.
Front Public Health . 2024 May; 12:1276391. PMID: 38784593
Introduction: More than 3 years into the pandemic, there is persisting uncertainty as to the etiology, biomarkers, and risk factors of Post COVID-19 Condition (PCC). Serological research data remain a...
4.
Trudel G, Stratis D, Rocheleau L, Pelchat M, Laneuville O
NPJ Microgravity . 2024 May; 10(1):55. PMID: 38740795
Space anemia affects astronauts and the underlying molecular alterations remain unknown. We evaluated the response of erythropoiesis-modulating genes to spaceflight through the analysis of leukocyte transcriptomes from astronauts during long-duration...
5.
Almeida N, Schiller I, Ke D, Sakr E, Plesa M, Vanamala S, et al.
Front Immunol . 2024 Mar; 15:1330549. PMID: 38433831
Background: Vaccination against COVID-19 is highly effective in preventing severe disease and hospitalization, but primary COVID mRNA vaccination schedules often differed from those recommended by the manufacturers due to supply...
6.
Azeez R, Lotoski L, Dubeau A, Rodriguez N, Reyna M, Freitas T, et al.
Epidemiol Health . 2023 Oct; 45:e2023091. PMID: 37857338
The coronavirus disease 2019 (COVID-19) pandemic has affected all Canadian families, with some impacted differently than others. Our study aims to: (1) determine the prevalence and transmission of severe acute...
7.
Whelan M, Galipeau Y, White-Al Habeeb N, Konforte D, Abou El Hassan M, Booth R, et al.
Open Forum Infect Dis . 2023 Aug; 10(8):ofad384. PMID: 37547857
Background: SARS-CoV-2 infections have disproportionally burdened elderly populations with excessive mortality. While several contributing factors exists, questions remain about the quality and duration of humoral antibody-mediated responses resulting from infections...
8.
Stratis D, Trudel G, Rocheleau L, Pelchat M, Laneuville O
Front Immunol . 2023 Jul; 14:1171103. PMID: 37426644
Introduction: Spaceflight leads to the deconditioning of multiple body systems including the immune system. We sought to characterize the molecular response involved by capturing changes in leukocyte transcriptomes from astronauts...
9.
Stratis D, Trudel G, Rocheleau L, Pelchat M, Laneuville O
Med Sci Sports Exerc . 2022 Oct; 55(3):365-375. PMID: 36251376
Introduction: We sought to isolate the microgravity effect of spaceflight from other space stressors by characterizing the leukocytes' transcriptome of participants to a 60-d bed rest study; an Earth model...
10.
Whelan M, Pelchat M
Viruses . 2022 Sep; 14(9). PMID: 36146833
The promoter-proximal pause induced by the binding of the DRB sensitivity-inducing factor (DSIF) and the negative elongation factor (NELF) to RNAP II is a key step in the regulation of...