Embryo Development and Gestation Using Fresh and Vitrified Oocytes

Overview

Journal Hum Reprod

Publisher Oxford University Press

Specialty Reproductive Medicine

Date 2010 Feb 27

PMID 20185514

Citations 23

Authors

Carlos Gilberto Almodin

Vania Cibele Minguetti-Camara

Cassia Lopes Paixao

Priscila Cardoso Pereira

Affiliations

Soon will be listed here.

Abstract

Background: The objective of this study was to compare the gestational results obtained with vitrified/thawed oocytes by a novel vitrification method (Vitri-ingá) to results obtained with fresh oocytes.

Methods: A total of 125 IVF-ET procedures carried out over 2008 were analysed, in which 79 patients received embryos from fresh oocytes (Group 1), and 46 patients received embryos from vitrified/thawed oocytes using Vitri-ingá (Group 2). Fresh and vitrified/thawed oocytes were fertilized and embryos were transferred. Fertilization, pregnancy and implantation rates were compared.

Results: Vitrified oocytes presented a survival rate of 84.9%. Fertilization, pregnancy and implantation rates showed no statistically significant differences between fresh and cryopreserved/thawed groups (81.3, 51.9, 21.3% and 80.8, 45.6 and 14.9%, respectively). Only the average number of blastomeres in Group 1 (6.86 +/- 2.07) was significantly higher than in Group 2 (6.35 +/- 2.26; P = 0.010).

Conclusions: Despite some differences in the patient groups, the clinical results of this study demonstrated that the Vitri-ingá method preserves the potential of human vitrified oocytes for fertilization and further development.

Citing Articles

Reply: Concerns regarding the study "Comparing the effects of a commercial and a prototype vitrification medium on meiotic spindle morphology and survival rate of mouse oocytes".

Viana I, Vireque A, Navarro P JBRA Assist Reprod. 2023; 27(3):582-583.

PMID: 37579269 PMC: 10712826. DOI: 10.5935/1518-0557.20230016.

The live birth rate of vitrified oocyte accumulation for managing diminished ovarian reserve: a retrospective cohort study.

Lee K, Lin M, Hwu Y, Yang J, Lee R J Ovarian Res. 2023; 16(1):49.

PMID: 36869354 PMC: 9983267. DOI: 10.1186/s13048-023-01128-y.

Concerns regarding the study "Comparing the effects of a commercial and a prototype vitrification medium on meiotic spindle morphology and survival rate of mouse oocytes".

Almodin C JBRA Assist Reprod. 2022; 26(4):679.

PMID: 36350243 PMC: 9635614. DOI: 10.5935/1518-0557.20220038.

A SART data cost-effectiveness analysis of planned oocyte cryopreservation versus in vitro fertilization with preimplantation genetic testing for aneuploidy considering ideal family size.

Bakkensen J, Flannagan K, Mumford S, Hutchinson A, Cheung E, Moreno P Fertil Steril. 2022; 118(5):875-884.

PMID: 36175208 PMC: 9613595. DOI: 10.1016/j.fertnstert.2022.07.022.

Comparing the effects of a commercial and a prototype vitrification medium on meiotic spindle morphology and survival rate of mouse oocytes.

Viana I, Vireque A, Navarro P JBRA Assist Reprod. 2022; 26(3):500-507.

PMID: 35261222 PMC: 9355432. DOI: 10.5935/1518-0557.20210117.