Lymphangiogenesis: Molecular Mechanisms and Future Promise

Overview

Journal Cell

Publisher Cell Press

Specialty Cell Biology

Date 2010 Feb 25

PMID 20178740

Citations 683

Authors

Tuomas Tammela

Kari Alitalo

Affiliations

Soon will be listed here.

Abstract

The growth of lymphatic vessels (lymphangiogenesis) is actively involved in a number of pathological processes including tissue inflammation and tumor dissemination but is insufficient in patients suffering from lymphedema, a debilitating condition characterized by chronic tissue edema and impaired immunity. The recent explosion of knowledge on the molecular mechanisms governing lymphangiogenesis provides new possibilities to treat these diseases.

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