Current Knowledge of the Pre-autophagosomal Structure (PAS)

Overview

Journal FEBS Lett

Specialty Biochemistry

Date 2010 Feb 9

PMID 20138172

Citations 93

Authors

Kuninori Suzuki

Yoshinori Ohsumi

Affiliations

Soon will be listed here.

Abstract

Autophagy is a system for degradation of bulk cellular components in lytic compartments, vacuoles, or lysosomes when eukaryotic cells face with nutrient starvation. In this review, we focus on the pre-autophagosomal structure (PAS), a functional entity responsible for autophagosome formation in Saccharomyces cerevisiae, and discuss its relevance to autophagy in mammalian cells.

Citing Articles

Emerging roles of ATG9/ATG9A in autophagy: implications for cell and neurobiology.

Choi J, Jang H, Xuan Z, Park D Autophagy. 2024; 20(11):2373-2387.

PMID: 39099167 PMC: 11572220. DOI: 10.1080/15548627.2024.2384349.

Ca2+-triggered Atg11-Bmh1/2-Snf1 complex assembly initiates autophagy upon glucose starvation.

Yao W, Chen Y, Zhang Y, Zhong S, Ye M, Chen Y J Cell Biol. 2024; 223(9.

PMID: 38980288 PMC: 11232891. DOI: 10.1083/jcb.202310049.

Autophagosome biogenesis and organelle homeostasis in plant cells.

Zhuang X, Li B, Jiang L Plant Cell. 2024; 36(9):3009-3024.

PMID: 38536783 PMC: 11371174. DOI: 10.1093/plcell/koae099.

Lv L, Yang C, Zhang X, Chen T, Luo M, Yu G Virulence. 2024; 15(1):2322183.

PMID: 38438325 PMC: 10913709. DOI: 10.1080/21505594.2024.2322183.

Impact of interorganelle coordination between the conventional early secretory pathway and autophagy in cellular homeostasis and stress response.

Tapia D, Cavieres V, Burgos P, Cancino J Front Cell Dev Biol. 2023; 11:1069256.

PMID: 37152281 PMC: 10160633. DOI: 10.3389/fcell.2023.1069256.