EXTra Hit for Mouse Osteochondroma

Overview

Journal Proc Natl Acad Sci U S A

Specialty Science

Date 2010 Feb 6

PMID 20133829

Citations 15

Authors

Judith V M G Bovee

Affiliations

Soon will be listed here.

Citing Articles

NFATC1 and NFATC2 expression patterns in human osteochondromas.

Wang Y, Ren J, Hou G, Ge X Heliyon. 2023; 9(1):e13018.

PMID: 36747924 PMC: 9898645. DOI: 10.1016/j.heliyon.2023.e13018.

Role of nuclear factor of activated T cells in chondrogenesis osteogenesis and osteochondroma formation.

Canalis E, Schilling L, Eller T, Yu J J Endocrinol Invest. 2022; 45(8):1507-1520.

PMID: 35352320 PMC: 10024159. DOI: 10.1007/s40618-022-01781-y.

The Close Relationship between the Golgi Trafficking Machinery and Protein Glycosylation.

Frappaolo A, Karimpour-Ghahnavieh A, Sechi S, Giansanti M Cells. 2020; 9(12).

PMID: 33321764 PMC: 7764369. DOI: 10.3390/cells9122652.

Hereditary multiple exostoses: are there new plausible treatment strategies?.

Pacifici M Expert Opin Orphan Drugs. 2019; 6(6):385-391.

PMID: 31448184 PMC: 6707746. DOI: 10.1080/21678707.2018.1483232.

NFAT restricts osteochondroma formation from entheseal progenitors.

Ge X, Tsang K, He L, Garcia R, Ermann J, Mizoguchi F JCI Insight. 2016; 1(4):e86254.

PMID: 27158674 PMC: 4855520. DOI: 10.1172/jci.insight.86254.

References

Hameetman L, Szuhai K, Yavas A, Knijnenburg J, van Duin M, van Dekken H . The role of EXT1 in nonhereditary osteochondroma: identification of homozygous deletions. J Natl Cancer Inst. 2007; 99(5):396-406. DOI: 10.1093/jnci/djk067. View

Clement A, Wiweger M, von der Hardt S, Rusch M, Selleck S, Chien C . Regulation of zebrafish skeletogenesis by ext2/dackel and papst1/pinscher. PLoS Genet. 2008; 4(7):e1000136. PMC: 2453328. DOI: 10.1371/journal.pgen.1000136. View

Stickens D, Zak B, Rougier N, Esko J, Werb Z . Mice deficient in Ext2 lack heparan sulfate and develop exostoses. Development. 2005; 132(22):5055-68. PMC: 2767329. DOI: 10.1242/dev.02088. View

Knudson Jr A . Mutation and cancer: statistical study of retinoblastoma. Proc Natl Acad Sci U S A. 1971; 68(4):820-3. PMC: 389051. DOI: 10.1073/pnas.68.4.820. View

Jones K, Piombo V, Searby C, Kurriger G, Yang B, Grabellus F . A mouse model of osteochondromagenesis from clonal inactivation of Ext1 in chondrocytes. Proc Natl Acad Sci U S A. 2010; 107(5):2054-9. PMC: 2836675. DOI: 10.1073/pnas.0910875107. View

Riminucci M, Saggio I, Robey P, Bianco P . Fibrous dysplasia as a stem cell disease. J Bone Miner Res. 2007; 21 Suppl 2:P125-31. DOI: 10.1359/jbmr.06s224. View

Reijmers R, Groen R, Rozemuller H, Kuil A, de Haan-Kramer A, Csikos T . Targeting EXT1 reveals a crucial role for heparan sulfate in the growth of multiple myeloma. Blood. 2009; 115(3):601-4. DOI: 10.1182/blood-2009-02-204396. View

Hall C, Cole W, Haynes R, Hecht J . Reevaluation of a genetic model for the development of exostosis in hereditary multiple exostosis. Am J Med Genet. 2002; 112(1):1-5. DOI: 10.1002/ajmg.10635. View

Bovee J, Cleton-Jansen A, Wuyts W, Caethoven G, Taminiau A, Bakker E . EXT-mutation analysis and loss of heterozygosity in sporadic and hereditary osteochondromas and secondary chondrosarcomas. Am J Hum Genet. 1999; 65(3):689-98. PMC: 1377975. DOI: 10.1086/302532. View

10.

Koziel L, Kunath M, Kelly O, Vortkamp A . Ext1-dependent heparan sulfate regulates the range of Ihh signaling during endochondral ossification. Dev Cell. 2004; 6(6):801-13. DOI: 10.1016/j.devcel.2004.05.009. View

11.

McCormick C, LEDUC Y, Martindale D, Mattison K, Esford L, Dyer A . The putative tumour suppressor EXT1 alters the expression of cell-surface heparan sulfate. Nat Genet. 1998; 19(2):158-61. DOI: 10.1038/514. View