Accuracy of 3 T MR Angioraphy in Vertebral Artery Stenosis and Coincidence with Other Cerebrovascular Stenoses

Overview

Journal Neuroradiology

Specialties Neurology
Radiology

Date 2010 Jan 29

PMID 20107775

Citations 1

Authors

Hyun Seok Choi

Dong Ik Kim

Dong Joon Kim

Jinna Kim

Eun Soo Kim

Seung-Koo Lee

Affiliations

Soon will be listed here.

Abstract

Introduction: Ostium of vertebral artery (VA) is a common site of pseudostenosis on contrast-enhanced MR angiography (CE-MRA). The purpose of this study was to determine the diagnostic accuracy of CE-MRA at 3 T in the evaluation of ostial stenosis of VA and to find associated coincidental stenoses using logistic regression analysis.

Methods: One hundred and thirty-five VA ostial regions from 72 patients who received CE-MRA of neck vessels, intracranial time of flight (TOF) MRA, and digital subtraction angiography (DSA) were retrospectively reviewed. The sensitivity and specificity of the CE-MRA in detection of ostial stenosis were calculated with reference standard of DSA. Ostial stenosis on MRA was correlated with coincidental lesions in intracranial and cervical arteries by logistic regression analysis.

Results: The sensitivity and specificity of the CE-MRA were 100% and 80.4% for detection of significant stenosis. In case of significant stenoses, CE-MRA showed a tendency of overestimation with a false-positive rate of 52.5%. Logistic regression analysis showed that the stenoses of middle cerebral artery (MCA) on TOF MRA was associated with significant stenoses of VA ostia (OR = 5.84, 95% confidence intervals 1.41-24.17).

Conclusion: CE-MRA is sensitive in detection of VA ostial stenosis although it has high false-positive rate. True positive ostial stenosis should be considered in cases of coincidental stenoses of MCA on TOF MRA.

Citing Articles

Increased risk for posterior circulation ischaemia in patients with vertebral artery hypoplasia: A systematic review and meta-analysis.

Katsanos A, Giannopoulos S Eur Stroke J. 2019; 2(2):171-177.

PMID: 31008312 PMC: 6453216. DOI: 10.1177/2396987317700540.

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