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Analysis of Stereotactic Vacuum-assisted Breast Biopsy for Patients with Segmental Calcifications

Overview
Journal Jpn J Radiol
Publisher Springer
Specialty Radiology
Date 2009 Dec 26
PMID 20035418
Authors
Kazuhiro Suzuki
Akihiko Shiraishi
Atsushi Arakawa
Affiliations
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Abstract

Purpose: To evaluate the results of stereotactic vacuum-assisted breast biopsy of segmental calcifications.

Material And Methods: Thirty-nine lesions with segmental calcifications after the exclusion of malignant calcifications of category 5 were evaluated. Calcifications were classified morphologically into small, round, and amorphous calcifications. Lesions in which small round and amorphous calcifications were mixed were classified into small round dominant and amorphous dominant calcifications. The density of distribution of calcifications, heterogeneity in size, and heterogeneity in density were also classified visually, and the correlations of these categories with the biopsy findings were evaluated.

Results: The calcifications were classified into 10 with small round calcifications (26%), 10 with small round calcifications dominant (26%), 12 with amorphous calcifications dominant (30%), and 7 with amorphous calcifications (18%). The pathological findings of biopsy specimens were benign in 27 lesions (69%), borderline in 1 (3%), and malignant in 11 (28%). Lesions with mixed calcifications in which amorphous calcifications were dominant were more often malignant. Lesions with calcifications showing a high distribution density and those with calcifications heterogeneous in density were more often malignant.

Conclusion: Lesions with heterogeneous calcifications are frequently malignant, and biopsy should be considered.

References
1.
Kettritz U, Rotter K, Schreer I, Murauer M, Schulz-Wendtland R, Peter D . Stereotactic vacuum-assisted breast biopsy in 2874 patients: a multicenter study. Cancer. 2004; 100(2):245-51. DOI: 10.1002/cncr.11887. View
2.
Hermann K, Obenauer S, Funke M, Grabbe E . Magnification mammography: a comparison of full-field digital mammography and screen-film mammography for the detection of simulated small masses and microcalcifications. Eur Radiol. 2002; 12(9):2188-91. DOI: 10.1007/s00330-002-1356-8. View
3.
Pijnappel R, Peeters P, Hendriks J, Mali W . Reproducibility of mammographic classifications for non-palpable suspect lesions with microcalcifications. Br J Radiol. 2004; 77(916):312-4. DOI: 10.1259/bjr/84593467. View
4.
Matsuzaki S, Shiba E, Kobayashi Y, Kawai M, Kitamura K, Nishita T . [Stereotactic vacuum-assisted breast biopsy (Mammotome biopsy) for non-palpable microcalcification on mammography]. Nihon Igaku Hoshasen Gakkai Zasshi. 2005; 65(1):16-22. View
5.
Verkooijen H . Diagnostic accuracy of stereotactic large-core needle biopsy for nonpalpable breast disease: results of a multicenter prospective study with 95% surgical confirmation. Int J Cancer. 2002; 99(6):853-9. DOI: 10.1002/ijc.10419. View