Worldwide Dissemination of the BlaOXA-23 Carbapenemase Gene of Acinetobacter Baumannii

Overview

Journal Emerg Infect Dis

Specialty Infectious Diseases

Date 2009 Dec 25

PMID 20031040

Citations 175

Authors

Pauline D Mugnier

Laurent Poirel

Thierry Naas

Patrice Nordmann

Affiliations

Soon will be listed here.

Abstract

To assess dissemination of OXA-23-producing strains of Acinetobacter baumannii, we obtained 20 carbapenem-resistant, OXA-23-producing isolates from different regions. Their clonal relationship was assessed by pulsed-field gel electrophoresis and multilocus sequence typing. We identified 8 sequence types, including 4 novel types. All except 2 strains belonged to 2 main European clonal lineages. The blaOXA-23 gene was either located on the chromosome or on plasmids and associated with 4 genetic structures.

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