Analysis of Naturally Occurring Avian Bornavirus Infection and Transmission During an Outbreak of Proventricular Dilatation Disease Among Captive Psittacine Birds

Overview

Journal J Virol

Publisher American Society for Microbiology

Date 2009 Dec 4

PMID 19955301

Citations 21

Authors

Amy L Kistler

Jeanne M Smith

Alexander L Greninger

Joseph L DeRisi

Don Ganem

Affiliations

Soon will be listed here.

Abstract

A proventricular dilatation disease (PDD) outbreak provided the opportunity to investigate the transmissibility of avian Bornavirus (ABV) and its linkage to PDD under natural conditions. Upon exposure to a bird with a fatal case of PDD, 10 birds became symptomatic and died. ABV2 RNA was recovered from available tissues. Further screening revealed that 12/46 exposed birds were ABV2(+). Three chicks boarded at this aviary developed PDD. They harbored the same ABV2 isolate and transmitted it to five of eight chicks in their home aviary. These findings demonstrate that ABV infection precedes the development of PDD. ABV-specific Western blotting and reverse transcription-PCR indicate that ABV2 is not strictly neurotropic.

Citing Articles

Surveillance of Parrot Bornavirus in Taiwan Captive .

Villanueva B, Chen J, Lin P, Minh H, Le V, Tyan Y Viruses. 2024; 16(5).

PMID: 38793686 PMC: 11125704. DOI: 10.3390/v16050805.

Molecular detection of bornavirus in parrots imported to China in 2022.

Zhang L, Huang Y, Liu H, Li L, Bai X, Yang G BMC Vet Res. 2023; 19(1):259.

PMID: 38057808 PMC: 10698882. DOI: 10.1186/s12917-023-03825-8.

A New Multiplex Real-Time RT-PCR for Simultaneous Detection and Differentiation of Avian Bornaviruses.

Sigrist B, Geers J, Albini S, Rubbenstroth D, Wolfrum N Viruses. 2021; 13(7).

PMID: 34372564 PMC: 8310230. DOI: 10.3390/v13071358.

Assessment of listing and categorisation of animal diseases within the framework of the Animal Health Law (Regulation (EU) No 2016/429): Borna disease.

More S, Botner A, Butterworth A, Calistri P, Depner K, Edwards S EFSA J. 2020; 15(7):e04951.

PMID: 32625602 PMC: 7009998. DOI: 10.2903/j.efsa.2017.4951.

Parrot bornavirus in naturally infected Brazilian captive parrots: Challenges in viral spread control.

Goncalves Silva A, Freitas Raso T, Costa E, Gomez S, da Silva Martins N PLoS One. 2020; 15(6):e0232342.

PMID: 32579594 PMC: 7313744. DOI: 10.1371/journal.pone.0232342.

References

Berhane Y, Smith D, Newman S, Taylor M, Nagy E, Binnington B . Peripheral neuritis in psittacine birds with proventricular dilatation disease. Avian Pathol. 2009; 30(5):563-70. DOI: 10.1080/03079450120078770. View

Vice C . Myocarditis as a component of psittacine proventricular dilatation syndrome in a Patagonian conure. Avian Dis. 1992; 36(4):1117-9. View

Honkavuori K, Shivaprasad H, Williams B, Quan P, Hornig M, Street C . Novel borna virus in psittacine birds with proventricular dilatation disease. Emerg Infect Dis. 2008; 14(12):1883-6. PMC: 2634650. DOI: 10.3201/eid1412.080984. View

Mannl A, Gerlach H, Leipold R . Neuropathic gastric dilatation in psittaciformes. Avian Dis. 1987; 31(1):214-21. View

Stitz L, Schilken D, Frese K . Atypical dissemination of the highly neurotropic Borna disease virus during persistent infection in cyclosporine A-treated, immunosuppressed rats. J Virol. 1991; 65(1):457-60. PMC: 240537. DOI: 10.1128/JVI.65.1.457-460.1991. View

Hallensleben W, Schwemmle M, Hausmann J, Stitz L, Volk B, Pagenstecher A . Borna disease virus-induced neurological disorder in mice: infection of neonates results in immunopathology. J Virol. 1998; 72(5):4379-86. PMC: 109668. DOI: 10.1128/JVI.72.5.4379-4386.1998. View

Weissenbock H, Sekulin K, Bakonyi T, Hogler S, Nowotny N . Novel avian bornavirus in a nonpsittacine species (Canary; Serinus canaria) with enteric ganglioneuritis and encephalitis. J Virol. 2009; 83(21):11367-71. PMC: 2772780. DOI: 10.1128/JVI.01343-09. View

Stitz L, Noske K, Planz O, Furrer E, Lipkin W, Bilzer T . A functional role for neutralizing antibodies in Borna disease: influence on virus tropism outside the central nervous system. J Virol. 1998; 72(11):8884-92. PMC: 110305. DOI: 10.1128/JVI.72.11.8884-8892.1998. View

Sullivan N, Mackie J, Miller R, Giles A . First case of psittacine proventricular dilatation syndrome (macaw wasting disease) in Australia. Aust Vet J. 1998; 75(9):674. DOI: 10.1111/j.1751-0813.1997.tb15371.x. View

10.

Doneley R, Miller R, Fanning T . Proventricular dilatation disease: an emerging exotic disease of parrots in Australia. Aust Vet J. 2007; 85(3):119-23. PMC: 7159114. DOI: 10.1111/j.1751-0813.2007.00109.x. View

11.

Kistler A, Gancz A, Clubb S, Skewes-Cox P, Fischer K, Sorber K . Recovery of divergent avian bornaviruses from cases of proventricular dilatation disease: identification of a candidate etiologic agent. Virol J. 2008; 5:88. PMC: 2546392. DOI: 10.1186/1743-422X-5-88. View

12.

Gancz A, Kistler A, Greninger A, Farnoushi Y, Mechani S, Perl S . Experimental induction of proventricular dilatation disease in cockatiels (Nymphicus hollandicus) inoculated with brain homogenates containing avian bornavirus 4. Virol J. 2009; 6:100. PMC: 2717941. DOI: 10.1186/1743-422X-6-100. View

13.

Daoust P, Julian R, Yason C, Artsob H . Proventricular impaction associated with nonsuppurative encephalomyelitis and ganglioneuritis in two Canada geese. J Wildl Dis. 1991; 27(3):513-7. DOI: 10.7589/0090-3558-27.3.513. View

14.

Weissenbock H, Bakonyi T, Sekulin K, Ehrensperger F, Doneley R, Durrwald R . Avian bornaviruses in psittacine birds from Europe and Australia with proventricular dilatation disease. Emerg Infect Dis. 2009; 15(9):1453-9. PMC: 2819881. DOI: 10.3201/eid1509.090353. View

15.

Rinder M, Ackermann A, Kempf H, Kaspers B, Korbel R, Staeheli P . Broad tissue and cell tropism of avian bornavirus in parrots with proventricular dilatation disease. J Virol. 2009; 83(11):5401-7. PMC: 2681939. DOI: 10.1128/JVI.00133-09. View

16.

Lutz M, Wilson R . Psittacine proventricular dilatation syndrome in an umbrella cockatoo. J Am Vet Med Assoc. 1991; 198(11):1962-4. View