Animal Virus Discovery: Improving Animal Health, Understanding Zoonoses, and Opportunities for Vaccine Development

Overview

Journal Curr Opin Virol

Publisher Elsevier

Specialty Microbiology

Date 2012 Apr 3

PMID 22463981

Citations 36

Authors

Eric Delwart

Affiliations

Soon will be listed here.

Abstract

The characterization of viral genomes has accelerated due to improvement in DNA sequencing technology. Sources of animal samples and molecular methods for the identification of novel viral pathogens and steps to determine their pathogenicity are listed. The difficulties for predicting future cross-species transmissions are highlighted by the wide diversity of known viral zoonoses. Recent surveys of viruses in wild and domesticated animals have characterized numerous viruses including some closely related to those infecting humans. The detection of multiple genetic lineages within viral families infecting a single host species, phylogenetically interspersed with viruses found in other host species, reflects past cross-species transmissions. Numerous opportunities for the generation of novel vaccines will arise from a better understanding of animal viromes.

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References

Wolfe N, Switzer W, Carr J, Bhullar V, Shanmugam V, Tamoufe U . Naturally acquired simian retrovirus infections in central African hunters. Lancet. 2004; 363(9413):932-7. DOI: 10.1016/S0140-6736(04)15787-5. View

Lauck M, Hyeroba D, Tumukunde A, Weny G, Lank S, Chapman C . Novel, divergent simian hemorrhagic fever viruses in a wild Ugandan red colobus monkey discovered using direct pyrosequencing. PLoS One. 2011; 6(4):e19056. PMC: 3081318. DOI: 10.1371/journal.pone.0019056. View

Phan T, Kapusinszky B, Wang C, Rose R, Lipton H, Delwart E . The fecal viral flora of wild rodents. PLoS Pathog. 2011; 7(9):e1002218. PMC: 3164639. DOI: 10.1371/journal.ppat.1002218. View

Parrish C, Holmes E, Morens D, Park E, Burke D, Calisher C . Cross-species virus transmission and the emergence of new epidemic diseases. Microbiol Mol Biol Rev. 2008; 72(3):457-70. PMC: 2546865. DOI: 10.1128/MMBR.00004-08. View

Blomstrom A . Viral metagenomics as an emerging and powerful tool in veterinary medicine. Vet Q. 2011; 31(3):107-14. DOI: 10.1080/01652176.2011.604971. View

Rose T, Schultz E, Henikoff J, Pietrokovski S, McCALLUM C, Henikoff S . Consensus-degenerate hybrid oligonucleotide primers for amplification of distantly related sequences. Nucleic Acids Res. 1998; 26(7):1628-35. PMC: 147464. DOI: 10.1093/nar/26.7.1628. View

Donaldson E, Haskew A, Gates J, Huynh J, Moore C, Frieman M . Metagenomic analysis of the viromes of three North American bat species: viral diversity among different bat species that share a common habitat. J Virol. 2010; 84(24):13004-18. PMC: 3004358. DOI: 10.1128/JVI.01255-10. View

Kapoor A, Mehta N, Esper F, Poljsak-Prijatelj M, Quan P, Qaisar N . Identification and characterization of a new bocavirus species in gorillas. PLoS One. 2010; 5(7):e11948. PMC: 2909267. DOI: 10.1371/journal.pone.0011948. View

VanDevanter D, Warrener P, Bennett L, Schultz E, Coulter S, Garber R . Detection and analysis of diverse herpesviral species by consensus primer PCR. J Clin Microbiol. 1996; 34(7):1666-71. PMC: 229091. DOI: 10.1128/JCM.34.7.1666-1671.1996. View

10.

Betsem E, Rua R, Tortevoye P, Froment A, Gessain A . Frequent and recent human acquisition of simian foamy viruses through apes' bites in central Africa. PLoS Pathog. 2011; 7(10):e1002306. PMC: 3203161. DOI: 10.1371/journal.ppat.1002306. View

11.

Luo Z, Roi S, Dastor M, Gallice E, Laurin M, LHomme Y . Multiple novel and prevalent astroviruses in pigs. Vet Microbiol. 2010; 149(3-4):316-23. PMC: 7172684. DOI: 10.1016/j.vetmic.2010.11.026. View

12.

Allander T, Tammi M, Eriksson M, Bjerkner A, Tiveljung-Lindell A, Andersson B . Cloning of a human parvovirus by molecular screening of respiratory tract samples. Proc Natl Acad Sci U S A. 2005; 102(36):12891-6. PMC: 1200281. DOI: 10.1073/pnas.0504666102. View

13.

Ng T, Willner D, Lim Y, Schmieder R, Chau B, Nilsson C . Broad surveys of DNA viral diversity obtained through viral metagenomics of mosquitoes. PLoS One. 2011; 6(6):e20579. PMC: 3108952. DOI: 10.1371/journal.pone.0020579. View

14.

Jones K, Patel N, Levy M, Storeygard A, Balk D, Gittleman J . Global trends in emerging infectious diseases. Nature. 2008; 451(7181):990-3. PMC: 5960580. DOI: 10.1038/nature06536. View

15.

Kapoor A, Mehta N, Dubovi E, Simmonds P, Govindasamy L, Medina J . Characterization of novel canine bocaviruses and their association with respiratory disease. J Gen Virol. 2011; 93(Pt 2):341-346. PMC: 3352345. DOI: 10.1099/vir.0.036624-0. View

16.

Chen E, Yagi S, Kelly K, Mendoza S, Tarara R, Canfield D . Cross-species transmission of a novel adenovirus associated with a fulminant pneumonia outbreak in a new world monkey colony. PLoS Pathog. 2011; 7(7):e1002155. PMC: 3136464. DOI: 10.1371/journal.ppat.1002155. View

17.

Wang D, Coscoy L, Zylberberg M, Avila P, Boushey H, Ganem D . Microarray-based detection and genotyping of viral pathogens. Proc Natl Acad Sci U S A. 2002; 99(24):15687-92. PMC: 137777. DOI: 10.1073/pnas.242579699. View

18.

Kapoor A, Li L, Victoria J, Oderinde B, Mason C, Pandey P . Multiple novel astrovirus species in human stool. J Gen Virol. 2009; 90(Pt 12):2965-2972. PMC: 2796194. DOI: 10.1099/vir.0.014449-0. View

19.

Kistler A, Avila P, Rouskin S, Wang D, Ward T, Yagi S . Pan-viral screening of respiratory tract infections in adults with and without asthma reveals unexpected human coronavirus and human rhinovirus diversity. J Infect Dis. 2007; 196(6):817-25. PMC: 7109683. DOI: 10.1086/520816. View

20.

Holmes E . What does virus evolution tell us about virus origins?. J Virol. 2011; 85(11):5247-51. PMC: 3094976. DOI: 10.1128/JVI.02203-10. View