ANCHOR: Web Server for Predicting Protein Binding Regions in Disordered Proteins

Overview

Journal Bioinformatics

Publisher Oxford University Press

Specialty Biology

Date 2009 Sep 1

PMID 19717576

Citations 289

Authors

Zsuzsanna Dosztanyi

Balint Meszaros

Istvan Simon

Affiliations

Soon will be listed here.

Abstract

Unlabelled: ANCHOR is a web-based implementation of an original method that takes a single amino acid sequence as an input and predicts protein binding regions that are disordered in isolation but can undergo disorder-to-order transition upon binding. The server incorporates the result of a general disorder prediction method, IUPred and can carry out simple motif searches as well.

Availability: The web server is available at http://anchor.enzim.hu. The program package is freely available for academic users.

Citing Articles

Machine learning approaches for predicting protein-ligand binding sites from sequence data.

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Evaluation of predictions of disordered binding regions in the CAID2 experiment.

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The strand exchange domain of tumor suppressor PALB2 is intrinsically disordered and promotes oligomerization-dependent DNA compaction.

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Accurate Prediction of Protein-Binding Residues in Protein Sequences Using SCRIBER.

Zhang J, Zhou F, Liang X, Kurgan L Methods Mol Biol. 2024; 2867:247-260.

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References

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