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Coumarins from Angelica Lucida L.--antibacterial Activities

Overview
Journal Molecules
Publisher MDPI
Specialty Biology
Date 2009 Aug 25
PMID 19701119
Citations 14
Authors
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Abstract

The first phytochemical investigation of the fruits of Angelica lucida has led to the isolation and characterization of five known coumarins (imperatorin, isoimperatorin, heraclenol, oxypeucedanin hydrate and heraclenin). All isolated compounds were identified by means of spectral and literature data. The extracts and the isolated constituents from A. lucida have been also evaluated for their antimicrobial activity against six Gram positive and negative bacteria, two oral pathogens and three human pathogenic fungi, exhibiting an interesting antimicrobial profile.

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References
1.
Kwon Y, Kobayashi A, Kajiyama S, Kawazu K, Kanzaki H, Kim C . Antimicrobial constituents of Angelica dahurica roots. Phytochemistry. 1997; 44(5):887-9. DOI: 10.1016/s0031-9422(96)00634-6. View

2.
Tada Y, Shikishima Y, Takaishi Y, Shibata H, Higuti T, Honda G . Coumarins and gamma-pyrone derivatives from Prangos pabularia: antibacterial activity and inhibition of cytokine release. Phytochemistry. 2002; 59(6):649-54. DOI: 10.1016/s0031-9422(02)00023-7. View

3.
Miftakhova A, Burasheva G, Abilov Z, Ahmad V, Zahid M . Coumarins from the aerial part of Halocnemum strobilaceum. Fitoterapia. 2001; 72(3):319-21. DOI: 10.1016/s0367-326x(00)00301-4. View

4.
Rosselli S, Maggio A, Bellone G, Formisano C, Basile A, Cicala C . Antibacterial and anticoagulant activities of coumarins isolated from the flowers of Magydaris tomentosa. Planta Med. 2006; 73(2):116-20. DOI: 10.1055/s-2006-951772. View

5.
Pasi S, Aligiannis N, Pratsinis H, Skaltsounis A, Chinou I . Biologically active triterpenoids from Cephalaria ambrosioides. Planta Med. 2009; 75(2):163-7. DOI: 10.1055/s-0028-1088391. View