Partial Reversion at the Bobbed Locus of Drosophila Melanogaster
Overview
Authors
Affiliations
In Drosophila melanogaster the tandemly arranged repetitive sequences coding for 18S and 28S rRNA are heterogenous at the level of the spacers between units and insertions that interrupt many 28S rRNA genes. This heterogeneity contrasts with the homogeneity of the regions transcribed into 18S and 28S rRNA. Homogenization and evolution of repetitive genes are usually explained by conversion, amplification events or unequal crossovers. In this paper we studied the change in rDNA patterns associated with partial reversion of bobbed mutations. In most cases, no increase in rDNA gene number, but a new repartition of gene types were found.
Bughio F, Maggert K Chromosome Res. 2018; 27(1-2):19-30.
PMID: 30511202 PMC: 6393165. DOI: 10.1007/s10577-018-9591-2.
Maggert K G3 (Bethesda). 2014; 4(3):497-507.
PMID: 24449686 PMC: 3962488. DOI: 10.1534/g3.113.008730.
Genetics: polymorphisms, epigenetics, and something in between.
Maggert K Genet Res Int. 2012; 2012:867951.
PMID: 22567405 PMC: 3335516. DOI: 10.1155/2012/867951.
Expression of I-CreI endonuclease generates deletions within the rDNA of Drosophila.
Paredes S, Maggert K Genetics. 2009; 181(4):1661-71.
PMID: 19171942 PMC: 2666528. DOI: 10.1534/genetics.108.099093.
Briscoe Jr A, Tomkiel J Genetics. 2000; 155(3):1195-211.
PMID: 10880481 PMC: 1461147. DOI: 10.1093/genetics/155.3.1195.