» Articles » PMID: 19687059

Current and Future Aberration Correctors for the Improvement of Resolution in Electron Microscopy

Overview
Date 2009 Aug 19
PMID 19687059
Citations 6
Authors
Affiliations
Soon will be listed here.
Abstract

The achievable resolution of a modern transmission electron microscope (TEM) is mainly limited by the inherent aberrations of the objective lens. Hence, one major goal over the past decade has been the development of aberration correctors to compensate the spherical aberration. Such a correction system is now available and it is possible to improve the resolution with this corrector. When high resolution in a TEM is required, one important parameter, the field of view, also has to be considered. In addition, especially for the large cameras now available, the compensation of off-axial aberrations is also an important task. A correction system to compensate the spherical aberration and the off-axial coma is under development. The next step to follow towards ultra-high resolution will be a correction system to compensate the chromatic aberration. With such a correction system, a new area will be opened for applications for which the chromatic aberration defines the achievable resolution, even if the spherical aberration is corrected. This is the case, for example, for low-voltage electron microscopy (EM) for the investigation of beam-sensitive materials, for dynamic EM or for in-situ EM.

Citing Articles

Direct Imaging of Radiation-Sensitive Organic Polymer-Based Nanocrystals at Sub-Ångström Resolution.

Carlino E, Taurino A, Hasa D, Bucar D, Polentarutti M, Chinchilla L Nanomaterials (Basel). 2024; 14(10).

PMID: 38786829 PMC: 11539949. DOI: 10.3390/nano14100872.


Single-particle cryo-EM at atomic resolution.

Nakane T, Kotecha A, Sente A, McMullan G, Masiulis S, Brown P Nature. 2020; 587(7832):152-156.

PMID: 33087931 PMC: 7611073. DOI: 10.1038/s41586-020-2829-0.


Aberration-corrected STEM imaging of 2D materials: Artifacts and practical applications of threefold astigmatism.

Lopatin S, Aljarb A, Roddatis V, Meyer T, Wan Y, Fu J Sci Adv. 2020; 6(37).

PMID: 32917685 PMC: 11206469. DOI: 10.1126/sciadv.abb8431.


Sub-2 Angstrom resolution structure determination using single-particle cryo-EM at 200 keV.

Wu M, Lander G, Herzik Jr M J Struct Biol X. 2020; 4:100020.

PMID: 32647824 PMC: 7337053. DOI: 10.1016/j.yjsbx.2020.100020.


Coherent Diffraction Imaging in Transmission Electron Microscopy for Atomic Resolution Quantitative Studies of the Matter.

Carlino E, Scattarella F, De Caro L, Giannini C, Siliqi D, Colombo A Materials (Basel). 2018; 11(11).

PMID: 30463217 PMC: 6266282. DOI: 10.3390/ma11112323.