Nanoscale Analysis of Supported Lipid Bilayers Using Atomic Force Microscopy

Overview

Journal Biochim Biophys Acta

Specialties Biochemistry
Biophysics

Date 2009 Aug 12

PMID 19664999

Citations 31

Authors

Karim El Kirat

Sandrine Morandat

Yves F Dufrene

Affiliations

Soon will be listed here.

Abstract

During the past 15 years, atomic force microscopy (AFM) has opened new opportunities for imaging supported lipid bilayers (SLBs) on the nanoscale. AFM offers a means to visualize the nanoscale structure of SLBs in physiological conditions. A unique feature of AFM is its ability to monitor dynamic events, like bilayer alteration, remodelling or digestion, upon incubation with various external agents such as drugs, detergents, proteins, peptides, nanoparticles, and solvents. Here, we survey recent progress made in the area.

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