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Angiographic Characteristics of the Coronary Artery in Patients with Type 2 Diabetes

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Date 2009 Aug 1
PMID 19644592
Citations 2
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Abstract

Objectives: To investigate the adverse effect of type 2 diabetes on coronary artery anatomy.

Patients And Methods: The coronary angiograms of 1564 consecutive patients were analyzed. The coronary lesions of patients with and without type 2 diabetes were compared.

Results: Seventy-four diabetic and 824 nondiabetic patients were found to have coronary artery disease. Diabetic patients had more multivessel (48.7% versus 34.7%, P<0.01), multilesion (64.9% versus 46.1%, P<0.05), extensive (51.4% versus 7.8%, P<0.01) and small vessel disease (95.2% versus 39.8%, P<0.01) than nondiabetic patients.

Conclusions: Type 2 diabetes is a significant risk factor for coronary artery disease. These findings may provide useful information for the future development of therapeutic strategies.

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References
1.
Herlitz J, Wognsen G, Karlson B, Sjoland H, Karlsson T, Caidahl K . Mortality, mode of death and risk indicators for death during 5 years after coronary artery bypass grafting among patients with and without a history of diabetes mellitus. Coron Artery Dis. 2000; 11(4):339-46. DOI: 10.1097/00019501-200006000-00007. View

2.
Stamler J, Vaccaro O, Neaton J, Wentworth D . Diabetes, other risk factors, and 12-yr cardiovascular mortality for men screened in the Multiple Risk Factor Intervention Trial. Diabetes Care. 1993; 16(2):434-44. DOI: 10.2337/diacare.16.2.434. View

3.
Abaci A, Oguzhan A, Kahraman S, Eryol N, Unal S, Arinc H . Effect of diabetes mellitus on formation of coronary collateral vessels. Circulation. 1999; 99(17):2239-42. DOI: 10.1161/01.cir.99.17.2239. View

4.
Schofer J, Schluter M, Rau T, Hammer F, Haag N, Mathey D . Influence of treatment modality on angiographic outcome after coronary stenting in diabetic patients: a controlled study. J Am Coll Cardiol. 2000; 35(6):1554-9. DOI: 10.1016/s0735-1097(00)00574-x. View

5.
Natali A, Vichi S, Landi P, Severi S, LAbbate A, Ferrannini E . Coronary atherosclerosis in Type II diabetes: angiographic findings and clinical outcome. Diabetologia. 2000; 43(5):632-41. DOI: 10.1007/s001250051352. View