Mechanisms of C-H Bond Activation: Rich Synergy Between Computation and Experiment

Overview

Journal Dalton Trans

Publisher Royal Society of Chemistry

Specialty Chemistry

Date 2009 Jul 23

PMID 19623381

Citations 35

Authors

Youcef Boutadla

David L Davies

Stuart A Macgregor

Amalia I Poblador-Bahamonde

Affiliations

Soon will be listed here.

Abstract

Recent computational studies of C-H bond activation at late transition metal systems are discussed and processes where lone pair assistance via heteroatom co-ligands or carboxylates are highlighted as a particularly promising means of cleaving C-H bonds. The term 'ambiphilic metal ligand activation' (AMLA) is introduced to describe such reactions.

Citing Articles

1,4-Pd Migration-Enabled Synthesis of Fused 4-Membered Rings.

Tsitopoulou M, Clemenceau A, Thesmar P, Baudoin O J Am Chem Soc. 2024; 146(28):18811-18816.

PMID: 38968581 PMC: 11258686. DOI: 10.1021/jacs.4c04701.

Electron Dynamics in Alkane C-H Activation Mediated by Transition Metal Complexes.

Cheng Y, Ho Y, Yang C, Chen C, Hsieh C, Cheng M J Phys Chem A. 2024; 128(23):4638-4650.

PMID: 38832757 PMC: 11182348. DOI: 10.1021/acs.jpca.4c01131.

Palladium (II)-Catalyzed C-H Activation with Bifunctional Ligands: From Curiosity to Industrialization.

Wu K, Lam N, Strassfeld D, Fan Z, Qiao J, Liu T Angew Chem Int Ed Engl. 2024; 63(19):e202400509.

PMID: 38419352 PMC: 11216193. DOI: 10.1002/anie.202400509.

Effect of α-Substitution on the Reactivity of C(sp)-H Bonds in Pd-Catalyzed C-H Arylation.

Wheatley M, Zuccarello M, Tsitopoulou M, Macgregor S, Baudoin O ACS Catal. 2023; 13(19):12563-12570.

PMID: 37822862 PMC: 10563019. DOI: 10.1021/acscatal.3c03806.

Opening a Pandora's Flask on a Prototype Catalytic Direct Arylation Reaction of Pentafluorobenzene: The AgCO/Pd(OAc)/PPh System.

Platt G, Aguiar P, Athavan G, Bray J, Scott N, Fairlamb I Organometallics. 2023; 42(17):2378-2394.

PMID: 37711884 PMC: 10498494. DOI: 10.1021/acs.organomet.3c00309.