Oxygenase Catalyzed 5-methylcytosine Hydroxylation

Overview

Journal Chem Biol

Publisher Elsevier

Specialties Biochemistry
Biology
Chemistry

Date 2009 Jun 25

PMID 19549596

Citations 31

Authors

Christoph Loenarz

Christopher J Schofield

Affiliations

Soon will be listed here.

Abstract

Recent reports identify the oxygenase catalyzed production of 5-hydroxymethylcytosine as a modification to mammalian DNA (Kriaucionis and Heintz, 2009; Tahiliani et al., 2009). This discovery has potential far-reaching implications for epigenetic regulation and will stimulate efforts to identify new nucleic acid modifications.

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