» Articles » PMID: 19524430

Nuclear Pore Complex Biogenesis

Overview
Publisher Elsevier
Specialty Cell Biology
Date 2009 Jun 16
PMID 19524430
Citations 29
Authors
Affiliations
Soon will be listed here.
Abstract

Nuclear pore complexes (NPCs) are the sole mediators of transport between the nucleus and the cytoplasm. NPCs have a life cycle: they assemble, disassemble, turnover, and age. The molecular mechanisms governing these different vital steps are beginning to emerge, suggesting key roles for the core structural scaffold of the NPC and auxiliary factors in the assembly of this large macromolecular complex, and connections between NPC maintenance, NPC turnover, and aging of the cell.

Citing Articles

An Analysis Regarding the Association Between the Nuclear Pore Complex (NPC) and Hepatocellular Carcinoma (HCC).

Huang P, Hu Y, Liu Y, Li J, Zhang Y J Hepatocell Carcinoma. 2023; 10:959-978.

PMID: 37377841 PMC: 10292625. DOI: 10.2147/JHC.S417501.


Tuning between Nuclear Organization and Functionality in Health and Disease.

Manda N, Golla U, Sesham K, Desai P, Joshi S, Patel S Cells. 2023; 12(5).

PMID: 36899842 PMC: 10000962. DOI: 10.3390/cells12050706.


Nuclear envelope budding and its cellular functions.

Keuenhof K, Kohler V, Broeskamp F, Panagaki D, Speese S, Buttner S Nucleus. 2023; 14(1):2178184.

PMID: 36814098 PMC: 9980700. DOI: 10.1080/19491034.2023.2178184.


Dark-Field Microscopic Study of Cellular Uptake of Carbon Nanodots: Nuclear Penetrability.

Zhang W, Ji Z, Zeng Z, Jayapalan A, Bagra B, Sheardy A Molecules. 2022; 27(8).

PMID: 35458634 PMC: 9032144. DOI: 10.3390/molecules27082437.


Uip4p modulates nuclear pore complex function in .

Deolal P, Jamir I, Mishra K Nucleus. 2022; 13(1):79-93.

PMID: 35171083 PMC: 8855845. DOI: 10.1080/19491034.2022.2034286.


References
1.
Maeshima K, Yahata K, Sasaki Y, Nakatomi R, Tachibana T, Hashikawa T . Cell-cycle-dependent dynamics of nuclear pores: pore-free islands and lamins. J Cell Sci. 2006; 119(Pt 21):4442-51. DOI: 10.1242/jcs.03207. View

2.
De Craene J, Coleman J, Estrada de Martin P, Pypaert M, Anderson S, Yates 3rd J . Rtn1p is involved in structuring the cortical endoplasmic reticulum. Mol Biol Cell. 2006; 17(7):3009-20. PMC: 1483037. DOI: 10.1091/mbc.e06-01-0080. View

3.
Heath I . Variant mitoses in lower eukaryotes: indicators of the evolution of mitosis. Int Rev Cytol. 2010; 64:1-80. DOI: 10.1016/s0074-7696(08)60235-1. View

4.
Franz C, Walczak R, Yavuz S, Santarella R, Gentzel M, Askjaer P . MEL-28/ELYS is required for the recruitment of nucleoporins to chromatin and postmitotic nuclear pore complex assembly. EMBO Rep. 2007; 8(2):165-72. PMC: 1796766. DOI: 10.1038/sj.embor.7400889. View

5.
Devos D, Dokudovskaya S, Williams R, Alber F, Eswar N, Chait B . Simple fold composition and modular architecture of the nuclear pore complex. Proc Natl Acad Sci U S A. 2006; 103(7):2172-7. PMC: 1413685. DOI: 10.1073/pnas.0506345103. View