High-speed Optical Frequency-domain Imaging

Overview

Journal Opt Express

Specialties Biophysics
Ophthalmology

Date 2009 May 28

PMID 19471415

Citations 197

Authors

S Yun

G Tearney

Johannes de Boer

N Iftimia

B Bouma

Affiliations

Soon will be listed here.

Abstract

We demonstrate high-speed, high-sensitivity, high-resolution optical imaging based on optical frequency-domain interferometry using a rapidly-tuned wavelength-swept laser. We derive and show experimentally that frequency-domain ranging provides a superior signal-to-noise ratio compared with conventional time-domain ranging as used in optical coherence tomography. A high sensitivity of -110 dB was obtained with a 6 mW source at an axial resolution of 13.5 microm and an A-line rate of 15.7 kHz, representing more than an order-of-magnitude improvement compared with previous OCT and interferometric imaging methods.

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References

Leitgeb R, Hitzenberger C, Fercher A . Performance of fourier domain vs. time domain optical coherence tomography. Opt Express. 2009; 11(8):889-94. DOI: 10.1364/oe.11.000889. View

Rollins A, Yazdanfar S, Kulkarni M, Ung-Arunyawee R, Izatt J . In vivo video rate optical coherence tomography. Opt Express. 2009; 3(6):219-29. DOI: 10.1364/oe.3.000219. View

Tearney G, Brezinski M, Bouma B, Boppart S, Pitris C, Southern J . In vivo endoscopic optical biopsy with optical coherence tomography. Science. 1997; 276(5321):2037-9. DOI: 10.1126/science.276.5321.2037. View

Golubovic B, Bouma B, Tearney G, Fujimoto J . Optical frequency-domain reflectometry using rapid wavelength tuning of a Cr4+:forsterite laser. Opt Lett. 2008; 22(22):1704-6. DOI: 10.1364/ol.22.001704. View

Chinn S, Swanson E, Fujimoto J . Optical coherence tomography using a frequency-tunable optical source. Opt Lett. 1997; 22(5):340-2. DOI: 10.1364/ol.22.000340. View

Huang D, Swanson E, Lin C, Schuman J, Stinson W, Chang W . Optical coherence tomography. Science. 1991; 254(5035):1178-81. PMC: 4638169. DOI: 10.1126/science.1957169. View

de Boer J, Srinivas S, Park B, Pham T, Chen Z, Milner T . Polarization Effects in Optical Coherence Tomography of Various Biological Tissues. IEEE J Sel Top Quantum Electron. 2015; 5(4):1200-1204. PMC: 4358303. DOI: 10.1109/2944.796347. View

Tearney G, Bouma B, Fujimoto J . High-speed phase- and group-delay scanning with a grating-based phase control delay line. Opt Lett. 2008; 22(23):1811-3. DOI: 10.1364/ol.22.001811. View

Youngquist R, Carr S, Davies D . Optical coherence-domain reflectometry: a new optical evaluation technique. Opt Lett. 2009; 12(3):158-60. DOI: 10.1364/ol.12.000158. View

10.

Lexer F, Hitzenberger C, Fercher A, Kulhavy M . Wavelength-tuning interferometry of intraocular distances. Appl Opt. 2008; 36(25):6548-53. DOI: 10.1364/ao.36.006548. View

11.

Yun S, Boudoux C, Tearney G, Bouma B . High-speed wavelength-swept semiconductor laser with a polygon-scanner-based wavelength filter. Opt Lett. 2003; 28(20):1981-3. DOI: 10.1364/ol.28.001981. View

12.

Tearney G, Yabushita H, Houser S, Aretz H, Jang I, Schlendorf K . Quantification of macrophage content in atherosclerotic plaques by optical coherence tomography. Circulation. 2003; 107(1):113-9. DOI: 10.1161/01.cir.0000044384.41037.43. View

13.

de Boer J, Cense B, Park B, Pierce M, Tearney G, Bouma B . Improved signal-to-noise ratio in spectral-domain compared with time-domain optical coherence tomography. Opt Lett. 2003; 28(21):2067-9. DOI: 10.1364/ol.28.002067. View

14.

Choma M, Sarunic M, Yang C, Izatt J . Sensitivity advantage of swept source and Fourier domain optical coherence tomography. Opt Express. 2009; 11(18):2183-9. DOI: 10.1364/oe.11.002183. View

15.

Ha Usler G, Lindner M . "Coherence radar" and "spectral radar"-new tools for dermatological diagnosis. J Biomed Opt. 2012; 3(1):21-31. DOI: 10.1117/1.429899. View

16.

Takada K, Yokohama I, Chida K, Noda J . New measurement system for fault location in optical waveguide devices based on an interferometric technique. Appl Opt. 2010; 26(9):1603-6. DOI: 10.1364/AO.26.001603. View