New Endoscopic and Cytologic Tools for Cancer Surveillance in the Digestive Tract

Overview

Journal Gastrointest Endosc Clin N Am

Specialties Gastroenterology
Pharmacology
Radiology

Date 2009 May 9

PMID 19423026

Citations 7

Authors

Eric J Seibel

Teresa A Brentnall

Jason A Dominitz

Affiliations

Soon will be listed here.

Abstract

Cancer surveillance is an increasing part of everyday practice in gastrointestinal Endoscopy due to the identification of high-risk groups from genetic and biomarker testing, genealogic and epidemiologic studies, and the increasing number of cancer survivors. An efficient surveillance program requires a cost-effective means for image-guided cancer detection and biopsy. A laser-based tethered-capsule endoscope with enhanced spectral imaging is introduced for unsedated surveillance of the lower esophagus. An ultrathin version of this same endoscope technology provides a 1.2-mm guidewire with imaging capability and cannula-style tools are proposed for image-guided biopsy. Advanced three-dimensional cell visualization techniques are described for increasing the sensitivity of early cancer diagnosis from hematoxylin-stained cells sampled from the pancreatic and biliary ducts.

Citing Articles

Advances in imaging technologies in the evaluation of high-grade bladder cancer.

Zlatev D, Altobelli E, Liao J Urol Clin North Am. 2015; 42(2):147-57, vii.

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Emerging endoscopic imaging technologies for bladder cancer detection.

Lopez A, Liao J Curr Urol Rep. 2014; 15(5):406.

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In vivo optical spectroscopy for improved detection of pancreatic adenocarcinoma: a feasibility study.

Lloyd W, Wilson R, Lee S, Chandra M, McKenna B, Simeone D Biomed Opt Express. 2014; 5(1):9-15.

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Color-matched and fluorescence-labeled esophagus phantom and its applications.

Yang C, Hou V, Nelson L, Seibel E J Biomed Opt. 2013; 18(2):26020.

PMID: 23403908 PMC: 3569733. DOI: 10.1117/1.JBO.18.2.026020.

Evaluation of a novel, ultrathin, tip-bending endoscope in a synthetic force-sensing pancreas with comparison to medical guide wires.

Chandler J, Lee C, Babchanik A, Melville C, Saunders M, Seibel E Med Devices (Auckl). 2012; 5:1-12.

PMID: 23166452 PMC: 3500967. DOI: 10.2147/MDER.S27439.

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