Creation of Functional Micro/nano Systems Through Top-down and Bottom-up Approaches

Overview

Journal Mol Cell Biomech

Specialties Biomedical Engineering
Cell Biology
Molecular Biology

Date 2009 Apr 23

PMID 19382535

Citations 14

Authors

Tak-Sing Wong

Branden Brough

Chih-Ming Ho

Affiliations

Soon will be listed here.

Abstract

Mimicking nature's approach in creating devices with similar functional complexity is one of the ultimate goals of scientists and engineers. The remarkable elegance of these naturally evolved structures originates from bottom-up self-assembly processes. The seamless integration of top-down fabrication and bottom-up synthesis is the challenge for achieving intricate artificial systems. In this paper, technologies necessary for guided bottom-up assembly such as molecular manipulation, molecular binding, and the self assembling of molecules will be reviewed. In addition, the current progress of synthesizing mechanical devices through top-down and bottom-up approaches will be discussed.

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