Overview of Antifungal Agents

Overview

Journal Clin Chest Med

Specialty Pulmonary Medicine

Date 2009 Apr 21

PMID 19375628

Citations 36

Authors

George R Thompson 3rd

Jose Cadena

Thomas F Patterson

Affiliations

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Abstract

This article is a comprehensive clinically focused review of currently available antifungals administered by way of the intravenous or inhalational route: amphotericin B and its lipid formulations, fluconazole, itraconazole, posaconazole, voriconazole, caspofungin, micafungin, anidulafungin, and flucytosine. Emphasis is placed on pharmacodynamics and kinetics, drug interactions, adverse events, and evidence for their use. Selected clinical trials demonstrating the efficacy of these agents are also reviewed.

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