Human Evoked Cortical Activity to Signal-to-noise Ratio and Absolute Signal Level

Overview

Journal Hear Res

Specialty Otorhinolaryngology

Date 2009 Apr 15

PMID 19364526

Citations 56

Authors

Curtis J Billings

Kelly L Tremblay

G Christopher Stecker

Wendy M Tolin

Affiliations

Soon will be listed here.

Abstract

The purpose of this study was to determine the effect of signal level and signal-to-noise ratio (SNR) on the latency and amplitude of evoked cortical activity to further our understanding of how the human central auditory system encodes signals in noise. Cortical auditory evoked potentials (CAEPs) were recorded from 15 young normal-hearing adults in response to a 1000 Hz tone presented at two tone levels in quiet and while continuous background noise levels were varied in five equivalent SNR steps. These 12 conditions were used to determine the effects of signal level and SNR level on CAEP components P1, N1, P2, and N2. Based on prior signal-in-noise experiments conducted in animals, we hypothesized that SNR, would be a key contributor to human CAEP characteristics. As hypothesized, amplitude increased and latency decreased with increasing SNR; in addition, there was no main effect of tone level across the two signal levels tested (60 and 75 dB SPL). Morphology of the P1-N1-P2 complex was driven primarily by SNR, highlighting the importance of noise when recording CAEPs. Results are discussed in terms of the current interest in recording CAEPs in hearing aid users.

Citing Articles

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References

Adler G, Adler J . Influence of stimulus intensity on AEP components in the 80- to 200-millisecond latency range. Audiology. 1989; 28(6):316-24. DOI: 10.3109/00206098909081638. View

Wolpaw J, PENRY J . A temporal component of the auditory evoked response. Electroencephalogr Clin Neurophysiol. 1975; 39(6):609-20. DOI: 10.1016/0013-4694(75)90073-5. View

Billings C, Tremblay K, Souza P, Binns M . Effects of hearing aid amplification and stimulus intensity on cortical auditory evoked potentials. Audiol Neurootol. 2007; 12(4):234-46. DOI: 10.1159/000101331. View

Rapin I, GRAZIANI L . Auditory-evoked responses in normal, brain-damaged, and deaf infants. Neurology. 1967; 17(9):881-94. DOI: 10.1212/wnl.17.9.881. View

Phillips D . Neural representation of sound amplitude in the auditory cortex: effects of noise masking. Behav Brain Res. 1990; 37(3):197-214. DOI: 10.1016/0166-4328(90)90132-x. View

Stapells D, Kurtzberg D . Evoked potential assessment of auditory system integrity in infants. Clin Perinatol. 1991; 18(3):497-518. View

BEAGLEY H, KNIGHT J . Changes in auditory evoked response with intensity. J Laryngol Otol. 1967; 81(8):861-73. DOI: 10.1017/s0022215100067815. View

Phillips D, Hall S . Spike-rate intensity functions of cat cortical neurons studied with combined tone-noise stimuli. J Acoust Soc Am. 1986; 80(1):177-87. DOI: 10.1121/1.394178. View

Robertson D, Irvine D . Plasticity of frequency organization in auditory cortex of guinea pigs with partial unilateral deafness. J Comp Neurol. 1989; 282(3):456-71. DOI: 10.1002/cne.902820311. View

10.

Caldwell M, Souza P, Tremblay K . Effect of probe tube insertion depth on spectral measures of speech. Trends Amplif. 2006; 10(3):145-54. PMC: 4111423. DOI: 10.1177/1084713806292653. View

11.

Davis H . Principles of electric response audiometry. Ann Otol Rhinol Laryngol. 1976; 85 SUPPL 28(3 Pt3):1-96. View

12.

Gibson D, Young E, Costalupes J . Similarity of dynamic range adjustment in auditory nerve and cochlear nuclei. J Neurophysiol. 1985; 53(4):940-58. DOI: 10.1152/jn.1985.53.4.940. View

13.

Kaplan-Neeman R, Kishon-Rabin L, Henkin Y, Muchnik C . Identification of syllables in noise: electrophysiological and behavioral correlates. J Acoust Soc Am. 2006; 120(2):926-33. DOI: 10.1121/1.2217567. View

14.

Phillips D . Temporal response features of cat auditory cortex neurons contributing to sensitivity to tones delivered in the presence of continuous noise. Hear Res. 1985; 19(3):253-68. DOI: 10.1016/0378-5955(85)90145-5. View

15.

Martin B, Tremblay K, Korczak P . Speech evoked potentials: from the laboratory to the clinic. Ear Hear. 2008; 29(3):285-313. DOI: 10.1097/AUD.0b013e3181662c0e. View

16.

Skrandies W . Data reduction of multichannel fields: global field power and principal component analysis. Brain Topogr. 1989; 2(1-2):73-80. DOI: 10.1007/BF01128845. View

17.

Bruneau N, Roux S, Garreau B, LELORD G . Frontal auditory evoked potentials and augmenting-reducing. Electroencephalogr Clin Neurophysiol. 1985; 62(5):364-71. DOI: 10.1016/0168-5597(85)90045-0. View

18.

Tremblay K, Kalstein L, Billings C, Souza P . The neural representation of consonant-vowel transitions in adults who wear hearing AIDS. Trends Amplif. 2006; 10(3):155-62. PMC: 4111424. DOI: 10.1177/1084713806292655. View

19.

Kraus N, McGee T . Mismatch Negativity in the Assessment of Central Auditory Function. Am J Audiol. 2015; 3(2):39-51. DOI: 10.1044/1059-0889.0302.39. View

20.

Phillips D, Kelly J . Effects of continuous noise maskers on tone-evoked potentials in cat primary auditory cortex. Cereb Cortex. 1992; 2(2):134-40. DOI: 10.1093/cercor/2.2.134. View