Selected Interventions in Nuclear Medicine: Gastrointestinal Motor Functions
Overview
Authors
Affiliations
The measurement of gastrointestinal functions by the use of scintigraphy is established in clinical practice and research. The most commonly used test is the gastric-emptying test, which is acknowledged as the gold standard to measure gastric motility and is conducted according to a consensus statement from the national nuclear medicine and motility societies. Other techniques are somewhat more esoteric (eg, measurement of gastric accommodation with single-photon emission computed tomography) or the scintigraphic approach is not the acknowledged gold standard (eg, colonic transit, rectoanal angle, and emptying, esophageal transit). The performance characteristics of many of the scintigraphic measurements have been published and the pros and cons established in the literature. Pharmacologic interventions may also be used during scintigraphy to aid in diagnosis and treatment. Gastrointestinal scintigraphy is an integral and important component of the assessment of gastrointestinal function.
McMahan Z, Tucker A, Perin J, Volkmann E, Kulkarni S, Ziessman H Arthritis Care Res (Hoboken). 2020; 74(3):442-450.
PMID: 33064934 PMC: 8050123. DOI: 10.1002/acr.24488.
In vitro evaluation of tc-99m radiopharmaceuticals for gastric emptying studies.
Ertay T, Dogan A, Ulker O, Durak H Mol Imaging Radionucl Ther. 2014; 23(1):21-4.
PMID: 24653931 PMC: 3957967. DOI: 10.4274/Mirt.75047.
Mariani G, Paglianiti I Eur J Nucl Med Mol Imaging. 2014; 41(3):405-7.
PMID: 24435771 DOI: 10.1007/s00259-013-2650-1.
Prucalopride: safety, efficacy and potential applications.
Quigley E Therap Adv Gastroenterol. 2012; 5(1):23-30.
PMID: 22282705 PMC: 3263983. DOI: 10.1177/1756283X11423706.
Baumann T, Kuesters S, Grueneberger J, Marjanovic G, Zimmermann L, Schaefer A Obes Surg. 2010; 21(1):95-101.
PMID: 21088924 DOI: 10.1007/s11695-010-0317-6.