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Neutralizing Anti-influenza Virus Monoclonal Antibodies: Therapeutics and Tools for Discovery

Overview
Journal Int Rev Immunol
Publisher Informa Healthcare
Date 2009 Feb 26
PMID 19241254
Citations 18
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Abstract

The human antibody response to influenza virus infection plays a protective role against re-infection, yet little molecular detail is available regarding how human antibodies, when characterized at the monoclonal level, neutralize this important human pathogen. Recent studies, using a diverse array of strategies, have isolated and characterized human anti-virus neutralizing antibodies and shed light not only on the specificity and origin of these antibodies but on their potential for therapeutic use against influenza virus infection.

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