Helical-ribbon Formation by a Beta-amino Acid Modified Amyloid Beta-peptide Fragment
Overview
Affiliations
An addition to the family: The introduction of beta-amino acid residues into a modified amyloid beta peptide fragment resulted in well-defined helical nanoribbons (see cryo-TEM image) comprising beta strands mainly oriented perpendicular to the ribbon axis. The nanoribbons order into a flow-aligning nematic phase at higher concentration. The beta-strand nanoribbon structure is an addition to the known set of secondary structures adopted by beta-peptides.
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