Who and Where is the Renal Baroreceptor?: the Connexin Hypothesis

Overview

Journal Kidney Int

Publisher Elsevier

Specialty Nephrology

Date 2009 Feb 17

PMID 19219002

Citations 15

Authors

R Ariel Gomez

Maria Luisa S Sequeira Lopez

Affiliations

Soon will be listed here.

Abstract

Gap junctions are emerging as a fundamental mechanism for the control of renin synthesis and release. Connexin40 is prominent in juxtaglomerular cells. When missing, it results in hyperreninemia and hypertension. Schweda et al. offer exciting data demonstrating that connexin45, a connexin with different biophysical properties, can replace connexin40 functions related to the control of renin.

Citing Articles

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