Sweetened Beverage Consumption and Risk of Coronary Heart Disease in Women

Overview

Journal Am J Clin Nutr

Publisher Elsevier

Specialty Nutritional Sciences

Date 2009 Feb 13

PMID 19211821

Citations 246

Authors

Teresa T Fung

Vasanti Malik

Kathryn M Rexrode

JoAnn E Manson

Walter C Willett

Frank B Hu

Affiliations

Soon will be listed here.

Abstract

Background: Previous studies have linked full-calorie sugar-sweetened beverages (SSBs) with greater weight gain and an increased risk of type 2 diabetes.

Objective: We prospectively examined the association between consumption of SSBs and the risk of coronary heart disease (CHD) in women.

Design: Women (n = 88,520) from the Nurses' Health Study aged 34-59 y, without previously diagnosed coronary heart disease (CHD), stroke, or diabetes in 1980, were followed from 1980 to 2004. Consumption of SSBs was derived from 7 repeated food-frequency questionnaires administered between 1980 and 2002. Relative risks (RRs) for CHD were calculated by using Cox proportional hazards models and adjusted for known cardiovascular disease risk factors.

Results: During 24 y of follow-up, we ascertained 3105 incident cases of CHD (nonfatal myocardial infarction and fatal CHD). After standard and dietary risk factors were adjusted for, the RRs (and 95% CIs) of CHD according to categories of cumulative average of SSB consumption (<1/mo, 1-4/mo, 2-6/wk, 1/d, and > or =2 servings/d) were 1.0, 0.96 (0.87, 1.06), 1.04 (0.95, 1.14), 1.23 (1.06, 1.43), and 1.35 (1.07, 1.69) (P for trend < 0.001). Additional adjustment for body mass index, energy intake, and incident diabetes attenuated the associations, but they remained significant. Artificially sweetened beverages were not associated with CHD.

Conclusion: Regular consumption of SSBs is associated with a higher risk of CHD in women, even after other unhealthful lifestyle or dietary factors are accounted for.

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References

Sarwar N, Danesh J, Eiriksdottir G, Sigurdsson G, Wareham N, Bingham S . Triglycerides and the risk of coronary heart disease: 10,158 incident cases among 262,525 participants in 29 Western prospective studies. Circulation. 2006; 115(4):450-8. DOI: 10.1161/CIRCULATIONAHA.106.637793. View

Nakagawa T, Tuttle K, Short R, Johnson R . Hypothesis: fructose-induced hyperuricemia as a causal mechanism for the epidemic of the metabolic syndrome. Nat Clin Pract Nephrol. 2006; 1(2):80-6. DOI: 10.1038/ncpneph0019. View

Basciano H, Federico L, Adeli K . Fructose, insulin resistance, and metabolic dyslipidemia. Nutr Metab (Lond). 2005; 2(1):5. PMC: 552336. DOI: 10.1186/1743-7075-2-5. View

Gao X, Qi L, Qiao N, Choi H, Curhan G, Tucker K . Intake of added sugar and sugar-sweetened drink and serum uric acid concentration in US men and women. Hypertension. 2007; 50(2):306-12. DOI: 10.1161/HYPERTENSIONAHA.107.091041. View

Janssens J, Shapira N, Debeuf P, Michiels L, Putman R, Bruckers L . Effects of soft drink and table beer consumption on insulin response in normal teenagers and carbohydrate drink in youngsters. Eur J Cancer Prev. 1999; 8(4):289-95. DOI: 10.1097/00008469-199908000-00004. View

Fung T, McCullough M, Newby P, Manson J, Meigs J, Rifai N . Diet-quality scores and plasma concentrations of markers of inflammation and endothelial dysfunction. Am J Clin Nutr. 2005; 82(1):163-73. DOI: 10.1093/ajcn.82.1.163. View

Palmer J, Boggs D, Krishnan S, Hu F, Singer M, Rosenberg L . Sugar-sweetened beverages and incidence of type 2 diabetes mellitus in African American women. Arch Intern Med. 2008; 168(14):1487-92. PMC: 2708080. DOI: 10.1001/archinte.168.14.1487. View

Dhingra R, Sullivan L, Jacques P, Wang T, Fox C, Meigs J . Soft drink consumption and risk of developing cardiometabolic risk factors and the metabolic syndrome in middle-aged adults in the community. Circulation. 2007; 116(5):480-8. DOI: 10.1161/CIRCULATIONAHA.107.689935. View

Johnson R, Segal M, Sautin Y, Nakagawa T, Feig D, Kang D . Potential role of sugar (fructose) in the epidemic of hypertension, obesity and the metabolic syndrome, diabetes, kidney disease, and cardiovascular disease. Am J Clin Nutr. 2007; 86(4):899-906. DOI: 10.1093/ajcn/86.4.899. View

10.

Salvini S, Hunter D, Sampson L, Stampfer M, Colditz G, Rosner B . Food-based validation of a dietary questionnaire: the effects of week-to-week variation in food consumption. Int J Epidemiol. 1989; 18(4):858-67. DOI: 10.1093/ije/18.4.858. View

11.

Fung T, Willett W, Stampfer M, Manson J, Hu F . Dietary patterns and the risk of coronary heart disease in women. Arch Intern Med. 2001; 161(15):1857-62. DOI: 10.1001/archinte.161.15.1857. View

12.

Yoo S, Nicklas T, Baranowski T, Zakeri I, Yang S, Srinivasan S . Comparison of dietary intakes associated with metabolic syndrome risk factors in young adults: the Bogalusa Heart Study. Am J Clin Nutr. 2004; 80(4):841-8. DOI: 10.1093/ajcn/80.4.841. View

13.

Sorensen L, Raben A, Stender S, Astrup A . Effect of sucrose on inflammatory markers in overweight humans. Am J Clin Nutr. 2005; 82(2):421-7. DOI: 10.1093/ajcn.82.2.421. View

14.

Ainsworth B, Haskell W, Whitt M, Irwin M, Swartz A, Strath S . Compendium of physical activities: an update of activity codes and MET intensities. Med Sci Sports Exerc. 2000; 32(9 Suppl):S498-504. DOI: 10.1097/00005768-200009001-00009. View

15.

Willerson J, Ridker P . Inflammation as a cardiovascular risk factor. Circulation. 2004; 109(21 Suppl 1):II2-10. DOI: 10.1161/01.CIR.0000129535.04194.38. View

16.

Malik V, Schulze M, Hu F . Intake of sugar-sweetened beverages and weight gain: a systematic review. Am J Clin Nutr. 2006; 84(2):274-88. PMC: 3210834. DOI: 10.1093/ajcn/84.1.274. View

17.

Liu S, Willett W, Stampfer M, Hu F, Franz M, Sampson L . A prospective study of dietary glycemic load, carbohydrate intake, and risk of coronary heart disease in US women. Am J Clin Nutr. 2000; 71(6):1455-61. DOI: 10.1093/ajcn/71.6.1455. View

18.

Bray G . How bad is fructose?. Am J Clin Nutr. 2007; 86(4):895-6. DOI: 10.1093/ajcn/86.4.895. View

19.

Schulze M, Manson J, Ludwig D, Colditz G, Stampfer M, Willett W . Sugar-sweetened beverages, weight gain, and incidence of type 2 diabetes in young and middle-aged women. JAMA. 2004; 292(8):927-34. DOI: 10.1001/jama.292.8.927. View

20.

Choi J, Ford E, Gao X, Choi H . Sugar-sweetened soft drinks, diet soft drinks, and serum uric acid level: the Third National Health and Nutrition Examination Survey. Arthritis Rheum. 2008; 59(1):109-16. DOI: 10.1002/art.23245. View