» Articles » PMID: 19191585

Antagonists of the P2X(7) Receptor. From Lead Identification to Drug Development

Overview
Journal J Med Chem
Specialty Chemistry
Date 2009 Feb 5
PMID 19191585
Citations 41
Authors
Affiliations
Soon will be listed here.
Citing Articles

Unlocking the therapeutic potential of P2X7 receptor: a comprehensive review of its role in neurodegenerative disorders.

Liu X, Li Y, Huang L, Kuang Y, Wu X, Ma X Front Pharmacol. 2024; 15:1450704.

PMID: 39139642 PMC: 11319138. DOI: 10.3389/fphar.2024.1450704.


Ionotropic purinergic receptor 7 (P2X7) channel structure and pharmacology provides insight regarding non-nucleotide agonism.

Al-Aqtash R, Collier D Channels (Austin). 2024; 18(1):2355150.

PMID: 38762911 PMC: 11110710. DOI: 10.1080/19336950.2024.2355150.


Leveraging the ATP-P2X7 receptor signalling axis to alleviate traumatic CNS damage and related complications.

Yin Y, Wei L, Caseley E, Lopez-Charcas O, Wei Y, Li D Med Res Rev. 2023; 43(5):1346-1373.

PMID: 36924449 PMC: 10947395. DOI: 10.1002/med.21952.


Nanobodies in cell-mediated immunotherapy: On the road to fight cancer.

Maali A, Gholizadeh M, Feghhi-Najafabadi S, Noei A, Seyed-Motahari S, Mansoori S Front Immunol. 2023; 14:1012841.

PMID: 36761751 PMC: 9905824. DOI: 10.3389/fimmu.2023.1012841.


Blocking P2X7 receptor with AZ 10606120 exacerbates vascular hyperpermeability and inflammation in murine polymicrobial sepsis.

Meegan J, Komalavilas P, Cheung-Flynn J, Yim T, Putz N, Jesse J Physiol Rep. 2022; 10(11):e15290.

PMID: 35668576 PMC: 9170948. DOI: 10.14814/phy2.15290.