» Articles » PMID: 19187183

Impact of Pharmacy Benefit Design on Prescription Drug Utilization: a Fixed Effects Analysis of Plan Sponsor Data

Overview
Journal Health Serv Res
Specialty Health Services
Date 2009 Feb 4
PMID 19187183
Citations 8
Authors
Affiliations
Soon will be listed here.
Abstract

Objective: To study the impact of various elements of pharmacy benefit design on both the absolute and relative utilization of generics, brands, retail pharmacy, and mail service.

Data Source: Panel data on 1,074 plan sponsors covering 21.6 million individuals over 12 calendar quarters (2005-2007).

Study Design: A retrospective analysis of pharmacy claims.

Statistical Methods: To control for potential endogeneity, linear fixed effects models were estimated for each of six dependent variables: the generic utilization rate, the brand utilization rate, the generic dispensing rate (GDR), the retail pharmacy utilization rate, the mail service utilization rate, and the mail distribution rate.

Principal Findings: Most member cost-share variables were nonlinearly associated with changes in prescription drug utilization. Marginal effects were generally greater in magnitude for brand out-of-pocket costs than for generic out-of-pocket costs. Time dummies, as well as other pharmacy benefit design elements, also yielded significant results.

Conclusions: Prior estimates of the effect of member cost sharing on prescription drug utilization may be biased if complex benefit designs, mail service fulfillment, and unmeasured factors such as pharmaceutical pipelines are not accounted for. Commonly cited relative utilization metrics, such as GDR, may be misleading if not examined alongside absolute prescription drug utilization.

Citing Articles

Factors Related to the Use of Topical vs. Oral NSAIDs for Sprains, Strains, and Contusions in a Senior Population: A Retrospective Analysis of Administrative Claims Data.

Sheer R, Schwab P, Noyes Essex M, Cappelleri J, Reiners A, Bobula J Drugs Aging. 2018; 35(10):937-950.

PMID: 30203313 DOI: 10.1007/s40266-018-0585-8.


Influencers of generic drug utilization: A systematic review.

Howard J, Harris I, Frank G, Kiptanui Z, Qian J, Hansen R Res Social Adm Pharm. 2017; 14(7):619-627.

PMID: 28814375 PMC: 5910277. DOI: 10.1016/j.sapharm.2017.08.001.


Impact of Cost Sharing on Therapeutic Substitution: The Story of Statins in 2006.

Li P, Schwartz J, Doshi J J Am Heart Assoc. 2016; 5(11).

PMID: 27836822 PMC: 5210334. DOI: 10.1161/JAHA.116.003377.


Estimating the Effect of Health Insurance on Personal Prescription Drug Importation.

Zullo A, Howe C, Galarraga O Med Care Res Rev. 2016; 74(2):178-207.

PMID: 26837427 PMC: 4970983. DOI: 10.1177/1077558716629039.


A comparison of drug formularies and the potential for cost-savings.

Kjos A, Schommer J, Yuan Y Am Health Drug Benefits. 2014; 3(5):321-30.

PMID: 25126325 PMC: 4106615.


References
1.
Gilman B, Kautter J . Impact of multitiered copayments on the use and cost of prescription drugs among Medicare beneficiaries. Health Serv Res. 2008; 43(2):478-95. PMC: 2442369. DOI: 10.1111/j.1475-6773.2007.00774.x. View

2.
Motheral B, Fairman K . Effect of a three-tier prescription copay on pharmaceutical and other medical utilization. Med Care. 2001; 39(12):1293-304. DOI: 10.1097/00005650-200112000-00005. View

3.
Landsman P, Yu W, Liu X, Teutsch S, Berger M . Impact of 3-tier pharmacy benefit design and increased consumer cost-sharing on drug utilization. Am J Manag Care. 2005; 11(10):621-8. View

4.
Huskamp H, Deverka P, Landrum M, Epstein R, McGuigan K . The effect of three-tier formulary adoption on medication continuation and spending among elderly retirees. Health Serv Res. 2007; 42(5):1926-42. PMC: 2254563. DOI: 10.1111/j.1475-6773.2007.00722.x. View

5.
Ellis R, Manning W . Optimal health insurance for prevention and treatment. J Health Econ. 2007; 26(6):1128-50. DOI: 10.1016/j.jhealeco.2007.09.002. View