Fast Disinfecting Antimicrobial Surfaces

Overview

Journal Langmuir

Publisher American Chemical Society

Specialty Chemistry

Date 2009 Jan 30

PMID 19177651

Citations 20

Authors

Ahmad E Madkour

Jeffery M Dabkowski

Klaus Nusslein

Gregory N Tew

Affiliations

Soon will be listed here.

Abstract

Silicon wafers and glass surfaces were functionalized with facially amphiphilic antimicrobial copolymers using the "grafting from" technique. Surface-initiated atom transfer radical polymerization (ATRP) was used to grow poly(butylmethacrylate)-co-poly(Boc-aminoethyl methacrylate) from the surfaces. Upon Boc-deprotection, these surfaces became highly antimicrobial and killed S. aureus and E. coli 100% in less than 5 min. The molecular weight and grafting density of the polymer were controlled by varying the polymerization time and initiator surface density. Antimicrobial studies showed that the killing efficiency of these surfaces was independent of polymer layer thickness or grafting density within the range of surfaces studied.

Citing Articles

Antimicrobial Polymer Surfaces Containing Quaternary Ammonium Centers (QACs): Synthesis and Mechanism of Action.

Santoro O, Izzo L Int J Mol Sci. 2024; 25(14).

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Contact Area and Deformation of Cells Adhered on a Cationic Surface.

Xu Z, Gamble A, Niu W, Smith M, Siegrist M, Tuominen M Langmuir. 2023; 39(18):6387-6398.

PMID: 37053037 PMC: 10685399. DOI: 10.1021/acs.langmuir.3c00089.

Effects of Neutral, Anionic and Cationic Polymer Brushes Grafted from Poly(para-phenylene vinylene) and Poly(para-phenylene ethynylene) on the Polymer's Photoluminescent Properties.

Kerr-Phillips T, Damavandi M, Pilkington L, Whitehead K, Travas-Sejdic J, Barker D Polymers (Basel). 2022; 14(14).

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Methacryloyl-GlcNAc Derivatives Copolymerized with Dimethacrylamide as a Novel Antibacterial and Biocompatible Coating.

Borgolte M, Riester O, Kacerova T, Rentschler S, Schmidt M, Jacksch S Pharmaceutics. 2021; 13(10).

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Self-Regenerating Antimicrobial Polymer Surfaces via Multilayer-Design - Sequential and Triggered Layer Shedding under Physiological Conditions.

Riga E, Gillies E, Lienkamp K Adv Mater Interfaces. 2021; 6(6).

PMID: 34405081 PMC: 7611505. DOI: 10.1002/admi.201802049.

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