A Comprehensive Overview of Radioguided Surgery Using Gamma Detection Probe Technology

Overview

Journal World J Surg Oncol

Publisher Biomed Central

Specialties General Surgery
Oncology

Date 2009 Jan 29

PMID 19173715

Citations 60

Authors

Stephen P Povoski

Ryan L Neff

Cathy M Mojzisik

David M OMalley

George H Hinkle

Nathan C Hall

Douglas A Murrey Jr

Michael V Knopp

Edward W Martin Jr

Affiliations

Soon will be listed here.

Abstract

The concept of radioguided surgery, which was first developed some 60 years ago, involves the use of a radiation detection probe system for the intraoperative detection of radionuclides. The use of gamma detection probe technology in radioguided surgery has tremendously expanded and has evolved into what is now considered an established discipline within the practice of surgery, revolutionizing the surgical management of many malignancies, including breast cancer, melanoma, and colorectal cancer, as well as the surgical management of parathyroid disease. The impact of radioguided surgery on the surgical management of cancer patients includes providing vital and real-time information to the surgeon regarding the location and extent of disease, as well as regarding the assessment of surgical resection margins. Additionally, it has allowed the surgeon to minimize the surgical invasiveness of many diagnostic and therapeutic procedures, while still maintaining maximum benefit to the cancer patient. In the current review, we have attempted to comprehensively evaluate the history, technical aspects, and clinical applications of radioguided surgery using gamma detection probe technology.

Citing Articles

Use of Radioguided Surgery for Small and Difficult-to-Locate Relapsed MIBG (+) High-Risk Neuroblastoma Lesions.

Krauel L, Pasten A, Gorostegui M, Mane S, Martin Gimenez M, Coronas M Cancers (Basel). 2024; 16(19).

PMID: 39409967 PMC: 11475745. DOI: 10.3390/cancers16193348.

Infrared Fluorescence-guided Surgery for Tumor and Metastatic Lymph Node Detection in Head and Neck Cancer.

White H, Naveed A, Campbell B, Lee Y, Baik F, Topf M Radiol Imaging Cancer. 2024; 6(4):e230178.

PMID: 38940689 PMC: 11287229. DOI: 10.1148/rycan.230178.

Translocator Protein 18 kDa (TSPO): A Promising Molecular Target for Image-Guided Surgery of Solid Cancers.

Wongso H, Kurniawan A, Setiadi Y, Kusumaningrum C, Widyasari E, Wibawa T Adv Pharm Bull. 2024; 14(1):86-104.

PMID: 38585455 PMC: 10997928. DOI: 10.34172/apb.2024.015.

First-in-human validation of a DROP-IN β-probe for robotic radioguided surgery: defining optimal signal-to-background discrimination algorithm.

Collamati F, Morganti S, van Oosterom M, Campana L, Ceci F, Luzzago S Eur J Nucl Med Mol Imaging. 2024; 51(10):3098-3108.

PMID: 38376805 PMC: 11300660. DOI: 10.1007/s00259-024-06653-6.

Steerable DROP-IN radioguidance during minimal-invasive non-robotic cervical and endometrial sentinel lymph node surgery.

van Oosterom M, Diaz-Feijoo B, Santisteban M, Sanchez-Izquierdo N, Perissinotti A, Glickman A Eur J Nucl Med Mol Imaging. 2024; 51(10):3089-3097.

PMID: 38233608 PMC: 11300633. DOI: 10.1007/s00259-023-06589-3.

References

Sortini D, Feo C, Carrella G, Bergossi L, Soliani G, Carcoforo P . Thoracoscopic localization techniques for patients with a single pulmonary nodule and positive oncological anamnesis: a prospective study. J Laparoendosc Adv Surg Tech A. 2004; 13(6):371-5. DOI: 10.1089/109264203322656432. View

Povoski S, Olsen J, Young D, Clarke J, Burak W, Walker M . Prospective randomized clinical trial comparing intradermal, intraparenchymal, and subareolar injection routes for sentinel lymph node mapping and biopsy in breast cancer. Ann Surg Oncol. 2006; 13(11):1412-21. DOI: 10.1245/s10434-006-9022-z. View

Haugen B . Management of the patient with progressive radioiodine non-responsive disease. Semin Surg Oncol. 1999; 16(1):34-41. DOI: 10.1002/(sici)1098-2388(199901/02)16:1<34::aid-ssu7>3.0.co;2-2. View

Rzyman W, Hagen O, Dziadziuszko R, Kobierska-Gulida G, Karmolinski A, Lothe I . Intraoperative, radio-guided sentinel lymph node mapping in 110 nonsmall cell lung cancer patients. Ann Thorac Surg. 2006; 82(1):237-42. DOI: 10.1016/j.athoracsur.2006.01.094. View

Gu J, Zhao J, Li Z, Yang Z, Zhang J, Gao Z . Clinical application of radioimmunoguided surgery in colorectal cancer using 125I-labeled carcinoembryonic antigen-specific monoclonal antibody submucosally. Dis Colon Rectum. 2003; 46(12):1659-66. DOI: 10.1007/BF02660772. View

Sarikaya I, Povoski S, Al-Saif O, Kocak E, Bloomston M, Marsh S . Combined use of preoperative 18F FDG-PET imaging and intraoperative gamma probe detection for accurate assessment of tumor recurrence in patients with colorectal cancer. World J Surg Oncol. 2007; 5:80. PMC: 1941735. DOI: 10.1186/1477-7819-5-80. View

Thelmo M, Morita E, Treseler P, Nguyen L, Allen Jr R, Sagebiel R . Micrometastasis to in-transit lymph nodes from extremity and truncal malignant melanoma. Ann Surg Oncol. 2001; 8(5):444-8. DOI: 10.1007/s10434-001-0444-3. View

Barranger E, Kerrou K, Petegnief Y, David-Montefiore E, Cortez A, Darai E . Laparoscopic resection of occult metastasis using the combination of FDG-positron emission tomography/computed tomography image fusion with intraoperative probe guidance in a woman with recurrent ovarian cancer. Gynecol Oncol. 2004; 96(1):241-4. DOI: 10.1016/j.ygyno.2004.09.030. View

Li B, Zhang W, Liu L, Wu L, Zhang R, Li N . Sentinel lymph node identification in patients with early stage cervical cancer undergoing radical hysterectomy and pelvic lymphadenectomy. Chin Med J (Engl). 2004; 117(6):867-70. View

10.

Sarlos D, Frey L, Haueisen H, Landmann G, Kots L, Schaer G . Radioguided occult lesion localization (ROLL) for treatment and diagnosis of malignant and premalignant breast lesions combined with sentinel node biopsy: a prospective clinical trial with 100 patients. Eur J Surg Oncol. 2008; 35(4):403-8. DOI: 10.1016/j.ejso.2008.06.016. View

11.

Barranger E, Cortez A, Commo F, Marpeau O, Uzan S, Darai E . Histopathological validation of the sentinel node concept in cervical cancer. Ann Oncol. 2004; 15(6):870-4. DOI: 10.1093/annonc/mdh227. View

12.

Desai D, Arnold M, Saha S, Hinkle G, Soble D, Fry J . Correlative Whole-Body FDG-PET and Intraoperative Gamma Detection of FDG Distribution in Colorectal Cancer. Clin Positron Imaging. 2001; 3(5):189-196. DOI: 10.1016/s1095-0397(00)00052-2. View

13.

Heij H, Rutgers E, de Kraker J, Vos A . Intraoperative search for neuroblastoma by MIBG and radioguided surgery with the gamma detector. Med Pediatr Oncol. 1997; 28(3):171-4. DOI: 10.1002/(sici)1096-911x(199703)28:3<171::aid-mpo2>3.0.co;2-g. View

14.

Salvatori M, Rufini V, Reale F, Samanes Gajate A, Maussier M, Revelli L . Radio-guided surgery for lymph node recurrences of differentiated thyroid cancer. World J Surg. 2003; 27(7):770-5. DOI: 10.1007/s00268-003-7014-8. View

15.

Landry C, McMasters K, Scoggins C . The evolution of the management of regional lymph nodes in melanoma. J Surg Oncol. 2007; 96(4):316-21. DOI: 10.1002/jso.20867. View

16.

Robinson . Radioisotope-Guided Surgical Biopsy of Suspected Osseous Metastases. Cancer Control. 2000; 4(6):516-522. DOI: 10.1177/107327489700400605. View

17.

Grebe S, Hay I . Thyroid cancer nodal metastases: biologic significance and therapeutic considerations. Surg Oncol Clin N Am. 1996; 5(1):43-63. View

18.

Federico A, Chagpar A, Ross M, Martin R, Noyes R, Goydos J . Effect of multiple-nodal basin drainage on cutaneous melanoma. Arch Surg. 2008; 143(7):632-7. DOI: 10.1001/archsurg.143.7.632. View

19.

Kosugi S, Nakagawa S, Kanda T, Odano I, Yajima K, Kaneko K . Radio-guided sentinel node mapping in patients with superficial esophageal carcinoma: feasibility study. Minim Invasive Ther Allied Technol. 2007; 16(3):181-6. DOI: 10.1080/13645700701384124. View

20.

Jimenez R, Panageas K, Busam K, Brady M . Prognostic implications of multiple lymphatic basin drainage in patients with truncal melanoma. J Clin Oncol. 2005; 23(3):518-24. DOI: 10.1200/JCO.2005.00.075. View