Validation of Attenuation Correction Using Transmission Truncation Compensation with a Small Field of View Dedicated Cardiac SPECT Camera System

Overview

Journal J Nucl Cardiol

Specialty Cardiology & Vascular Diseases

Date 2009 Jan 22

PMID 19156477

Citations 3

Authors

Gavin L Noble

Alan W Ahlberg

Aravind Rao Kokkirala

S James Cullom

Timothy M Bateman

Giselle M Cyr

Deborah M Katten

Glenn D Tadeo

James A Case

David M OSullivan

Gary V Heller

Affiliations

Soon will be listed here.

Abstract

Background: Although attenuation correction (AC) has been successfully applied to large field of view (LFOV) cameras, applicability to small field of view (SFOV) cameras is a concern due to truncation. This study compared perfusion images between a LFOV and SFOV camera with truncation compensation, using the same AC solution.

Methods And Results: Seventy-eight clinically referred patients underwent rest-stress single-photon emission computed tomography (SPECT) using both a SFOV and LFOV camera in a randomized sequence. Blinded images were interpreted by a consensus of three experienced readers. The percentage of normal images for SFOV and LFOV was significantly higher with than without AC (72% vs 44% and 72% vs 49%, both P < .001). Interpretive agreement between cameras was better with than without AC (kappa = 0.736 to 0.847 vs 0.545 to 0.774). Correlation for the summed stress score was higher with than without AC (r (2) = 0.892 vs 0.851, both P < 0.001) while Bland Altman analysis demonstrated narrower limits with than without AC (4.0 to -4.3 vs 5.9 to -5.6).

Conclusion: Attenuation correction using truncation compensation with a SFOV camera yields similar results to a LFOV camera. The higher interpretive agreement between cameras after attenuation correction suggests that such images are preferable to non-attenuation-corrected images.

Citing Articles

Diagnostic accuracy of high-resolution attenuation-corrected Anger-camera SPECT in the detection of coronary artery disease.

Patil H, Bateman T, McGhie A, Burgett E, Courter S, Case J J Nucl Cardiol. 2013; 21(1):127-34.

PMID: 24259153 DOI: 10.1007/s12350-013-9817-9.

A multicenter evaluation of a new post-processing method with depth-dependent collimator resolution applied to full-time and half-time acquisitions without and with simultaneously acquired attenuation correction.

Venero C, Heller G, Bateman T, McGhie A, Ahlberg A, Katten D J Nucl Cardiol. 2009; 16(5):714-25.

PMID: 19582531 DOI: 10.1007/s12350-009-9106-9.

Multicenter investigation comparing a highly efficient half-time stress-only attenuation correction approach against standard rest-stress Tc-99m SPECT imaging.

Bateman T, Heller G, McGhie A, Courter S, Golub R, Case J J Nucl Cardiol. 2009; 16(5):726-35.

PMID: 19548048 DOI: 10.1007/s12350-009-9109-6.

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