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Intestinal Hormones and Growth Factors: Effects on the Small Intestine

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Specialty Gastroenterology
Date 2009 Jan 20
PMID 19152442
Citations 28
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Abstract

There are various hormones and growth factors which may modify the intestinal absorption of nutrients, and which might thereby be useful in a therapeutic setting, such as in persons with short bowel syndrome. In part I, we focus first on insulin-like growth factors, epidermal and transferring growth factors, thyroid hormones and glucocorticosteroids. Part II will detail the effects of glucagon-like peptide (GLP)-2 on intestinal absorption and adaptation, and the potential for an additive effect of GLP2 plus steroids.

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References
1.
Scott R, Kirk D, Macnaughton W, Meddings J . GLP-2 augments the adaptive response to massive intestinal resection in rat. Am J Physiol. 1998; 275(5):G911-21. DOI: 10.1152/ajpgi.1998.275.5.G911. View

2.
Dvorak B, Stephana A, Holubec H, Williams C, Philipps A, Koldovskoy O . Insulin-like growth factor-I (IGF-I) mRNA in the small intestine of suckling and adult rats. FEBS Lett. 1996; 388(2-3):155-60. DOI: 10.1016/0014-5793(96)00495-4. View

3.
Mason H, Carr L, Leake R, Franks S . Production of transforming growth factor-alpha by normal and polycystic ovaries. J Clin Endocrinol Metab. 1995; 80(7):2053-6. DOI: 10.1210/jcem.80.7.7608254. View

4.
Divine J, McCaul S, Simon T . HNF-1alpha and endodermal transcription factors cooperatively activate Fabpl: MODY3 mutations abrogate cooperativity. Am J Physiol Gastrointest Liver Physiol. 2003; 285(1):G62-72. DOI: 10.1152/ajpgi.00074.2003. View

5.
Freeman B, Yamamoto K . Disassembly of transcriptional regulatory complexes by molecular chaperones. Science. 2002; 296(5576):2232-5. DOI: 10.1126/science.1073051. View