Development and Evaluation of a Computerized Test Battery for Alzheimer's Disease Screening in Community-based Settings

Overview

Journal Am J Alzheimers Dis Other Demen

Publisher Sage Publications

Specialty Neurology

Date 2009 Jan 20

PMID 19150968

Citations 21

Authors

Masashi Inoue

Daiki Jinbo

Yuka Nakamura

Miyako Taniguchi

Katsuya Urakami

Affiliations

Soon will be listed here.

Abstract

Aim: To evaluate the capability of a computerized test battery for Alzheimer's disease screening which has been newly developed to provide a standardized and efficient method for widespread use in routine clinical and community-based settings.

Methods: Participants were 72 individuals diagnosed with Alzheimer's disease and 102 healthy elderly individuals. Both groups were tested by the battery. Receiver operating characteristic analysis was used to examine the ability of the battery to differentiate between those with Alzheimer's disease and cognitively healthy elderly individuals.

Results: On a group level, the Alzheimer's disease group performed worse than the control group on each of the 4 computerized test tasks. Receiver operating characteristic analysis yielded maximum sensitivity and specificity values of 96% and 86% for total scores, respectively.

Conclusion: We believe the battery is very useful for routine clinical and community-based settings.

Citing Articles

Subjective Difficulty with Higher-Level Functional Capacity in Community-Dwelling Older People withMild Cognitive Impairment.

Shiba Y, Anzai S, Ueda T, Sasa N, Yamagami T, Omori Y Fukushima J Med Sci. 2024; 70(4):183-192.

PMID: 39370275 PMC: 11625852. DOI: 10.5387/fms.23-00013.

Research on digital tool in cognitive assessment: a bibliometric analysis.

Chen L, Zhen W, Peng D Front Psychiatry. 2023; 14:1227261.

PMID: 37680449 PMC: 10482043. DOI: 10.3389/fpsyt.2023.1227261.

Cross-Sectional Association between Estimated Hardness of the Habitual Diet and Depressive Symptoms in Older Japanese Men.

Fujiwara A, Fukunaga A, Murakami K, Inoue Y, Nakagawa T, Yamamoto S Nutrients. 2023; 15(13).

PMID: 37447360 PMC: 10346684. DOI: 10.3390/nu15133034.

Suggestions on the ideal method of conducting community screenings for older adults.

Kouzuki M, Tanaka N, Miyamoto M, Urakami K BMC Geriatr. 2023; 23(1):397.

PMID: 37380967 PMC: 10308771. DOI: 10.1186/s12877-023-04119-2.

Association between Dietary Hardness and Cognitive Dysfunction among Japanese Men in Their 60s: A Cross-Sectional Study.

Fujiwara A, Fukunaga A, Murakami K, Inoue Y, Nakagawa T, Yamamoto S Nutrients. 2023; 15(11).

PMID: 37299449 PMC: 10255220. DOI: 10.3390/nu15112485.

References

Shulman K . Clock-drawing: is it the ideal cognitive screening test?. Int J Geriatr Psychiatry. 2000; 15(6):548-61. DOI: 10.1002/1099-1166(200006)15:6<548::aid-gps242>3.0.co;2-u. View

W Barker W, Luis C, Harwood D, Loewenstein D, Bravo M, Ownby R . The effect of a memory screening program on the early diagnosis of Alzheimer disease. Alzheimer Dis Assoc Disord. 2005; 19(1):1-7. DOI: 10.1097/01.wad.0000155380.63231.68. View

Dwolatzky T, Whitehead V, Doniger G, Simon E, Schweiger A, Jaffe D . Validity of the Mindstreams computerized cognitive battery for mild cognitive impairment. J Mol Neurosci. 2004; 24(1):33-44. DOI: 10.1385/jmn:24:1:033. View

Solomon P, Hirschoff A, Kelly B, Relin M, BRUSH M, DeVeaux R . A 7 minute neurocognitive screening battery highly sensitive to Alzheimer's disease. Arch Neurol. 1998; 55(3):349-55. DOI: 10.1001/archneur.55.3.349. View

Robbins T, James M, Owen A, Sahakian B, McInnes L, Rabbitt P . Cambridge Neuropsychological Test Automated Battery (CANTAB): a factor analytic study of a large sample of normal elderly volunteers. Dementia. 1994; 5(5):266-81. DOI: 10.1159/000106735. View

Solomon P, Murphy C . Should we screen for Alzheimer's disease? A review of the evidence for and against screening Alzheimer's disease in primary care practice. Geriatrics. 2005; 60(11):26-31. View

Knopman D . Current treatment of mild cognitive impairment and Alzheimer's disease. Curr Neurol Neurosci Rep. 2006; 6(5):365-71. DOI: 10.1007/s11910-996-0016-9. View

Bennett D, Schneider J, Arvanitakis Z, Kelly J, Aggarwal N, Shah R . Neuropathology of older persons without cognitive impairment from two community-based studies. Neurology. 2006; 66(12):1837-44. DOI: 10.1212/01.wnl.0000219668.47116.e6. View

Mendiondo M, Ashford J, Kryscio R, Schmitt F . Designing a Brief Alzheimer Screen (BAS). J Alzheimers Dis. 2003; 5(5):391-8. DOI: 10.3233/jad-2003-5506. View

10.

Trenkle D, Shankle W, Azen S . Detecting cognitive impairment in primary care: performance assessment of three screening instruments. J Alzheimers Dis. 2007; 11(3):323-35. DOI: 10.3233/jad-2007-11309. View

11.

Gualtieri C, Johnson L . Reliability and validity of a computerized neurocognitive test battery, CNS Vital Signs. Arch Clin Neuropsychol. 2006; 21(7):623-43. DOI: 10.1016/j.acn.2006.05.007. View

12.

Letz R, Green R, Woodard J . Development of a computer-based battery designed to screen adults for neuropsychological impairment. Neurotoxicol Teratol. 1996; 18(4):365-70. DOI: 10.1016/0892-0362(96)00041-4. View

13.

Welsh K, Fillenbaum G, Wilkinson W, HEYMAN A, Mohs R, Stern Y . Neuropsychological test performance in African-American and white patients with Alzheimer's disease. Neurology. 1995; 45(12):2207-11. DOI: 10.1212/wnl.45.12.2207. View

14.

Buschke H, Kuslansky G, Katz M, Stewart W, Sliwinski M, Eckholdt H . Screening for dementia with the memory impairment screen. Neurology. 1999; 52(2):231-8. DOI: 10.1212/wnl.52.2.231. View

15.

Kobak K, Taylor L, Dottl S, Greist J, Jefferson J, Burroughs D . A computer-administered telephone interview to identify mental disorders. JAMA. 1997; 278(11):905-10. View

16.

Green R, Green J, Harrison J, Kutner M . Screening for cognitive impairment in older individuals. Validation study of a computer-based test. Arch Neurol. 1994; 51(8):779-86. DOI: 10.1001/archneur.1994.00540200055017. View

17.

Ganguli M, Rodriguez E, Mulsant B, Richards S, Pandav R, Vander Bilt J . Detection and management of cognitive impairment in primary care: The Steel Valley Seniors Survey. J Am Geriatr Soc. 2004; 52(10):1668-75. DOI: 10.1111/j.1532-5415.2004.52459.x. View

18.

Ivanoiu A, Adam S, Van der Linden M, Salmon E, Juillerat A, Mulligan R . Memory evaluation with a new cued recall test in patients with mild cognitive impairment and Alzheimer's disease. J Neurol. 2005; 252(1):47-55. DOI: 10.1007/s00415-005-0597-2. View

19.

Doniger G, Zucker D, Schweiger A, Dwolatzky T, Chertkow H, Crystal H . Towards practical cognitive assessment for detection of early dementia: a 30-minute computerized battery discriminates as well as longer testing. Curr Alzheimer Res. 2005; 2(2):117-24. DOI: 10.2174/1567205053585792. View

20.

Ross G, Abbott R, Petrovitch H, Masaki K, Murdaugh C, Trockman C . Frequency and characteristics of silent dementia among elderly Japanese-American men. The Honolulu-Asia Aging Study. JAMA. 1997; 277(10):800-5. View