A New Role for Cisplatin: Probing Ribosomal RNA Structure

Overview

Journal Chem Commun (Camb)

Publisher Royal Society of Chemistry

Specialty Chemistry

Date 2008 Dec 17

PMID 19082014

Citations 20

Authors

Keshab Rijal

Christine S Chow

Affiliations

Soon will be listed here.

Abstract

In this study, cisplatin, the well-known anticancer drug, was used to probe accessible purine residues in E. coli 16S ribosomal RNA (rRNA), free or in the context of 30S subunits or 70S ribosomes, both in vitro and in vivo.

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