Identification and Characterization of Class 1 Integron Resistance Gene Cassettes Among Salmonella Strains Isolated from Imported Seafood

Overview

Journal Appl Environ Microbiol

Specialties Environmental Health
Microbiology

Date 2008 Dec 17

PMID 19074612

Citations 10

Authors

Ashraf A Khan

Elizabeth Ponce

M S Nawaz

Chorng-Ming Cheng

Junaid A Khan

Christine S West

Affiliations

Soon will be listed here.

Abstract

A total of 210 Salmonella isolates, representing 64 different serovars, were isolated from imported seafood samples, and 55/210 isolates were found to be resistant to at least one antibiotic. Class 1 integrons from three multidrug-resistant Salmonella enterica strains (Salmonella enterica serovars Newport [strain 62], Typhimurium var. Copenhagen [strain 629], and Lansing [strain 803], originating from Hong Kong, the Philippines, and Taiwan, respectively) were characterized. Southern hybridization of plasmids isolated from these strains, using a class 1 integron probe, showed that trimethoprim-sulfamethoxazole and streptomycin resistance genes were located on a megaplasmid in strain 629. Our study indicates that imported seafood could be a reservoir for Salmonella isolates resistant to multiple antibiotics.

Citing Articles

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