Cycle Changing the Medium Results in Increased Nisin Productivity Per Cell in Lactococcus Lactis

Overview

Journal Biotechnol Lett

Specialties Biochemistry
Biotechnology

Date 2008 Nov 29

PMID 19039524

Citations 4

Authors

Omer Simsek

Per E J Saris

Affiliations

Soon will be listed here.

Abstract

High specific cellular nisin production was aimed by cycle changing the medium of Lactococcus lactis N8 and LAC48. The highest level of nisin production was reached with the 120 min cycles but maximal production was unstable. In shorter cycles (30 and 60 min) cells could be maintained in a high production state up to the end of the fermentation (28 and 14 cycles). N8 produced 19-fold and LAC48 15-fold more nisin with cycle changing the medium than without cycle incubation.

Citing Articles

Effect of Soy Protein Products on Growth and Metabolism of , , and .

Wen W, Hu M, Gao Y, Zhang P, Meng W, Zhang F Foods. 2024; 13(10).

PMID: 38790825 PMC: 11121397. DOI: 10.3390/foods13101525.

A Point Mutation in Cassette Relieves the Repression Regulation of CcpA Resulting in an Increase in the Degradation of 2,3-Butanediol in .

Xu X, Liu F, Qiao W, Dong Y, Yang H, Liu F Microorganisms. 2024; 12(4).

PMID: 38674718 PMC: 11051896. DOI: 10.3390/microorganisms12040773.

Genomic Features and Construction of Streamlined Genome Chassis of Nisin Z Producer N8.

Qiao W, Liu F, Wan X, Qiao Y, Li R, Wu Z Microorganisms. 2022; 10(1).

PMID: 35056496 PMC: 8779420. DOI: 10.3390/microorganisms10010047.

Nisin production in a chitin-including continuous fermentation system with Lactococcus lactis displaying a cell wall chitin-binding domain.

Simsek O J Ind Microbiol Biotechnol. 2013; 41(3):535-43.

PMID: 24342966 DOI: 10.1007/s10295-013-1388-x.