The GTPase Superfamily: Conserved Structure and Molecular Mechanism

Overview

Journal Nature

Specialty Science

Date 1991 Jan 10

PMID 1898771

Citations 1004

Authors

H R Bourne

D A Sanders

F McCormick

Affiliations

Soon will be listed here.

Abstract

GTPases are conserved molecular switches, built according to a common structural design. Rapidly accruing knowledge of individual GTPases--crystal structures, biochemical properties, or results of molecular genetic experiments--support and generate hypotheses relating structure to function in other members of the diverse family of GTPases.

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