Bite Force and Pattern Measurements for Dental Pain Assessment in the Rat

Overview

Journal Neurosci Lett

Specialty Neurology

Date 2008 Oct 18

PMID 18926882

Citations 8

Authors

Junad Khan

Rafael Benoliel

Uri Herzberg

Andrew J Mannes

Robert M Caudle

Andrew Young

Eli Eliav

Affiliations

Soon will be listed here.

Abstract

We present simple method to assess dental pain in the awake rat. Using a sensitive strain gauge we examined changes in bite strength and bite pattern in rats following dental injury. Rats with dental injury displayed a significant reduction in mean peak bite strength and an altered bite cluster pattern. Both changes in the dental injury rats were reversed by an analgesic dose of morphine, and this could be reversed with naloxone. These changes were not observed in naive control animals. This simple method significantly improves our ability to evaluate dental pain syndromes.

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