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In Vitro Culture Under Physiologic Oxygen Concentration Improves Blastocyst Yield and Quality: a Prospective Randomized Survey on Sibling Oocytes

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Journal Fertil Steril
Date 2008 Aug 30
PMID 18722608
Citations 34
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Abstract

A prospective randomized study was carried on sibling oocytes in which human gametes and embryos were cultured at physiologic (6% CO(2) + 5% O(2) + 89% N(2)) condition from insemination to day 6 or at atmospheric (6% CO(2) in air) condition until day 3 and at physiologic environment afterward. The results showed that physiologic oxygen concentration throughout culture period improved total blastocyst yield and day 5 embryo quality.

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