Hypotony Maculopathy in a Patient with HLA-B27-associated Uveitis

Purpose: To describe a patient with HLA-B27-associated anterior uveitis who developed hypotony maculopathy.

Methods: Visual acuity, biomicroscopic slit-lamp examination, and fluorescein angiogram.

Results: Following an episode of acute anterior nongranulomatous HLA-B27-associated uveitis, the patient developed decreased vision, choroidal folds, optic disc edema, and a serous exudative detachment characteristic of hypotony maculopathy. The intraocular pressure was noted to be 4 mmHg. Following therapy with topical 1% prednisolone acetate and 5% homatropine, both the intraocular pressure and retinal anatomy normalized.

Conclusions: Hypotony maculopathy may be seen in patients with HLA-B27-associated uveitis and should be considered as a cause of vision loss in patients with this condition.