Evaluation of Surgical Outcomes and Gallbladder Characteristics in Patients with Biliary Dyskinesia

Overview

Journal J Gastrointest Surg

Specialty Gastroenterology

Date 2008 Jun 11

PMID 18543048

Citations 10

Authors

M Shirin Sabbaghian

Barrie S Rich

Gary D Rothberger

Jonathan Cohen

Steven Batash

Elissa Kramer

H Leon Pachter

Stuart G Marcus

Peter Shamamian

Affiliations

Soon will be listed here.

Abstract

Introduction: This study was designed to compare symptomatic outcomes following cholecystectomy in patients with biliary dyskinesia.

Materials And Methods: From 1999 to 2006 at New York University Medical Center, 197 adults underwent hepatobiliary scintigraphy with cholecystokinin administration to evaluate gallbladder ejection fraction (GBEF). Biliary dyskinesia was demonstrated in 120 patients based on decreased GBEF of </=35%. Forty-four patients underwent cholecystectomy, and data from chart review and telephone questionnaires were available for 42 patients. Patients reported symptomatic improvement whether gallstones were present (25/27, 92.6%) or absent (13/15, 86.7%) prior to cholecystectomy (p = 0.90). The most common pathologic findings were chronic cholecystitis and cholesterolosis, regardless of the presence of gallstones. Additional data from 101 of the 120 patients with decreased GBEF demonstrated 74/101 (73.2%) patients were diagnosed with gastroesophageal reflux disease (GERD), and 59/101 (58.4%) patients were diagnosed with gastritis.

Results: The results of this study suggest that biliary dyskinesia should be considered as part of the spectrum of symptomatic gallbladder disease that can be successfully treated with cholecystectomy and that biliary dyskinesia is associated with GERD and gastritis.

Citing Articles

Role of Cholecystectomy in Symptomatic Hyperkinetic Gallbladder Patients.

Singh J Case Rep Surg. 2021; 2021:5569850.

PMID: 33833891 PMC: 8016577. DOI: 10.1155/2021/5569850.

Role of laparoscopic cholecystectomy in the management of chronic right upper quadrant pain due to biliary dyskinesia: a systematic review and meta-analysis.

Rehman S, Singh K, Sajid M Transl Gastroenterol Hepatol. 2019; 4:71.

PMID: 31620653 PMC: 6789200. DOI: 10.21037/tgh.2019.08.10.

Is hyperkinetic gallbladder an indication for cholecystectomy?.

Saurabh S, Green B Surg Endosc. 2018; 33(5):1613-1617.

PMID: 30209609 DOI: 10.1007/s00464-018-6435-2.

Cholecystectomy for biliary dyskinesia: how did we get there?.

Bielefeldt K, Saligram S, Zickmund S, Dudekula A, Olyaee M, Yadav D Dig Dis Sci. 2014; 59(12):2850-63.

PMID: 25193389 DOI: 10.1007/s10620-014-3342-9.

Pain provocation and low gallbladder ejection fraction with CCK cholescintigraphy are not predictive of chronic acalculous gallbladder disease symptom relief after cholecystectomy.

Edwards M, Mullenbach B, Chamberlain S Dig Dis Sci. 2014; 59(11):2773-8.

PMID: 24852884 DOI: 10.1007/s10620-014-3213-4.

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