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High-level Resistance to Cefotaxime and Ceftazidime in Klebsiella Pneumoniae Isolates from Cleveland, Ohio

Overview
Specialty Pharmacology
Date 1991 May 1
PMID 1854155
Citations 12
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Abstract

Two isolates of Klebsiella pneumoniae possessing both TEM-1 and SHV-2 beta-lactamases were isolated from patients at the Cleveland Clinic in 1988. The beta-lactamases were discriminated and identified by using substrate hydrolysis data and an isoelectric focusing procedure in which the gel was overlaid with beta-lactamase inhibitors.

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