Xenohormesis: Sensing the Chemical Cues of Other Species

Overview

Journal Cell

Publisher Cell Press

Specialty Cell Biology

Date 2008 May 6

PMID 18455976

Citations 102

Authors

Konrad T Howitz

David A Sinclair

Affiliations

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Abstract

Many plant molecules interact with and modulate key regulators of mammalian physiology in ways that are beneficial to health, but why? We propose that heterotrophs (animals and fungi) are able to sense chemical cues synthesized by plants and other autotrophs in response to stress. These cues provide advance warning about deteriorating environmental conditions, allowing the heterotrophs to prepare for adversity while conditions are still favorable.

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